A NEW AND EFFICIENT PREPARATION OF ALPHA,BETA-DEHYDROAMINO ACIDS

K  GOODALL; A F  PARSONS

A NEW AND EFFICIENT PREPARATION OF ALPHA,BETA-DEHYDROAMINO ACIDS

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A new one-pot synthesis of dehydroamino acids has been developed by reaction of beta-hydroxy-alpha-amino acids with dichloroacetyl chloride and a tertiary amine base. The reaction proceeds in 58-89% yield.

Original language	English
Pages (from-to)	3259-3260
Number of pages	2
Journal	Tetrahedron Letters
Volume	36
Issue number	18
Publication status	Published - 1 May 1995

Keywords

STEREOSPECIFIC SYNTHESIS
DEHYDROALANINE PEPTIDES
DERIVATIVES

Cite this

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title = "A NEW AND EFFICIENT PREPARATION OF ALPHA,BETA-DEHYDROAMINO ACIDS",

abstract = "A new one-pot synthesis of dehydroamino acids has been developed by reaction of beta-hydroxy-alpha-amino acids with dichloroacetyl chloride and a tertiary amine base. The reaction proceeds in 58-89% yield.",

keywords = "STEREOSPECIFIC SYNTHESIS, DEHYDROALANINE PEPTIDES, DERIVATIVES",

author = "K GOODALL and PARSONS, {A F}",

year = "1995",

month = may,

day = "1",

language = "English",

volume = "36",

pages = "3259--3260",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "18",

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TY - JOUR

T1 - A NEW AND EFFICIENT PREPARATION OF ALPHA,BETA-DEHYDROAMINO ACIDS

AU - GOODALL, K

AU - PARSONS, A F

PY - 1995/5/1

Y1 - 1995/5/1

N2 - A new one-pot synthesis of dehydroamino acids has been developed by reaction of beta-hydroxy-alpha-amino acids with dichloroacetyl chloride and a tertiary amine base. The reaction proceeds in 58-89% yield.

AB - A new one-pot synthesis of dehydroamino acids has been developed by reaction of beta-hydroxy-alpha-amino acids with dichloroacetyl chloride and a tertiary amine base. The reaction proceeds in 58-89% yield.

KW - STEREOSPECIFIC SYNTHESIS

KW - DEHYDROALANINE PEPTIDES

KW - DERIVATIVES

M3 - Article

SN - 0040-4039

VL - 36

SP - 3259

EP - 3260

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 18

ER -