A NEW APPROACH TO RETINOIDS VIA ORGANOMETALLIC ADDITION TO PYRYLIUM-SALTS

K  HEMMING; E F  DEMEDEIROS; R J K  TAYLOR

A NEW APPROACH TO RETINOIDS VIA ORGANOMETALLIC ADDITION TO PYRYLIUM-SALTS

K HEMMING, E F DEMEDEIROS, R J K TAYLOR

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

Original language	English
Pages (from-to)	2623-2624
Number of pages	2
Journal	JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Issue number	22
Publication status	Published - 21 Nov 1994

Keywords

VITAMIN-A

Cite this

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title = "A NEW APPROACH TO RETINOIDS VIA ORGANOMETALLIC ADDITION TO PYRYLIUM-SALTS",

abstract = "A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.",

keywords = "VITAMIN-A",

author = "K HEMMING and DEMEDEIROS, {E F} and TAYLOR, {R J K}",

year = "1994",

month = nov,

day = "21",

language = "English",

pages = "2623--2624",

journal = "JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS",

issn = "0022-4936",

publisher = "Chemical Society",

number = "22",

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AU - HEMMING, K

AU - DEMEDEIROS, E F

AU - TAYLOR, R J K

PY - 1994/11/21

Y1 - 1994/11/21

N2 - A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

AB - A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

KW - VITAMIN-A

M3 - Article

SN - 0022-4936

SP - 2623

EP - 2624

JO - JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

JF - JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

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ER -