By the same authors

From the same journal

From the same journal

A new era in palaeomicrobiology: prospects for ancient dental calculus as a long-term record of the human oral microbiome

Research output: Contribution to journalArticle

Full text download(s)

Published copy (DOI)

Author(s)

Department/unit(s)

Publication details

JournalPhilosophical Transactions Of The Royal Society Of London Series B - Biological Sciences
DateE-pub ahead of print - 8 Dec 2014
DatePublished (current) - Jan 2015
Issue number1660
Volume370
Early online date8/12/14
Original languageEnglish

Abstract

The field of palaeomicrobiology is dramatically expanding thanks to recent advances in high-throughput biomolecular sequencing, which allows unprecedented access to the evolutionary history and ecology of human-associated and environmental microbes. Recently, human dental calculus has been shown to be an abundant, nearly ubiquitous, and long-term reservoir of the ancient oral microbiome, preserving not only microbial and host biomolecules but also dietary and environmental debris. Modern investigations of native human microbiota have demonstrated that the human microbiome plays a central role in health and chronic disease, raising questions about changes in microbial ecology, diversity and function through time. This paper explores the current state of ancient oral microbiome research and discusses successful applications, methodological challenges and future possibilities in elucidating the intimate evolutionary relationship between humans and their microbes.

Bibliographical note

© 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations