A new mild radical route to 3-substituted maleimides using organoboroles

Peter Birch, Andrew F. Parsons*, Paul Cross

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A new, mild, radical route for the synthesis of 3-substituted maleimides has been developed. This new method incorporates alkene hydroboration, conjugate addition-aminoxylation and TEMPO-H elimination in a one-pot procedure, using cheap, readily available starting materials. A variety of 3-substituted maleimides have been prepared in good to excellent yield.

Original languageEnglish
Pages (from-to)822-824
Number of pages3
JournalTetrahedron Letters
Issue number7
Publication statusPublished - 15 Feb 2012

Bibliographical note

Funding Information:
We would like to thank the EPSRC and Cytec Engineered Materials for funding.


  • Addition
  • Elimination
  • Maleimide
  • Organoborole
  • Radical

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