A new mild radical route to 3-substituted maleimides using organoboroles

Peter Birch; Andrew F. Parsons; Paul Cross

doi:10.1016/j.tetlet.2011.12.012

A new mild radical route to 3-substituted maleimides using organoboroles

Peter Birch, Andrew F. Parsons^*, Paul Cross

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A new, mild, radical route for the synthesis of 3-substituted maleimides has been developed. This new method incorporates alkene hydroboration, conjugate addition-aminoxylation and TEMPO-H elimination in a one-pot procedure, using cheap, readily available starting materials. A variety of 3-substituted maleimides have been prepared in good to excellent yield.

Original language	English
Pages (from-to)	822-824
Number of pages	3
Journal	Tetrahedron Letters
Volume	53
Issue number	7
DOIs	https://doi.org/10.1016/j.tetlet.2011.12.012
Publication status	Published - 15 Feb 2012

Bibliographical note

Funding Information:
We would like to thank the EPSRC and Cytec Engineered Materials for funding.

Keywords

Addition
Elimination
Maleimide
Organoborole
Radical

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10.1016/j.tetlet.2011.12.012

Cite this

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abstract = "A new, mild, radical route for the synthesis of 3-substituted maleimides has been developed. This new method incorporates alkene hydroboration, conjugate addition-aminoxylation and TEMPO-H elimination in a one-pot procedure, using cheap, readily available starting materials. A variety of 3-substituted maleimides have been prepared in good to excellent yield.",

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AU - Parsons, Andrew F.

AU - Cross, Paul

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Y1 - 2012/2/15

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KW - Addition

KW - Elimination

KW - Maleimide

KW - Organoborole

KW - Radical

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ER -

A new mild radical route to 3-substituted maleimides using organoboroles

Abstract

Bibliographical note

Keywords

Access to Document

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