A NEW ROUTE TO 2E,4E-DIENALS FROM ORGANOMETALLIC REAGENTS VIA A 5-CARBON HOMOLOGATION PROCESS

N  LEWIS; P W  MCKEN; R J K  TAYLOR

A NEW ROUTE TO 2E,4E-DIENALS FROM ORGANOMETALLIC REAGENTS VIA A 5-CARBON HOMOLOGATION PROCESS

N LEWIS, P W MCKEN, R J K TAYLOR

Chemistry

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

A new procedure for the preparation of 2E,4E-dienals 4 is described based on the addition of organometallic reagents to silylated glutaconaldehyde 2 [(2E,4E)-5-trialkylsiloxy-2,4-pentadienal] as a five-carbon synthon. Application of the methodology to the synthesis of two dienamide natural products (pellitorine and sarmentine) are discussed.

Original language	English
Pages (from-to)	898-900
Number of pages	3
Journal	Synlett
Issue number	12
Publication status	Published - Dec 1991

Keywords

CARBONYL-COMPOUNDS
ALDEHYDES

Cite this

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title = "A NEW ROUTE TO 2E,4E-DIENALS FROM ORGANOMETALLIC REAGENTS VIA A 5-CARBON HOMOLOGATION PROCESS",

abstract = "A new procedure for the preparation of 2E,4E-dienals 4 is described based on the addition of organometallic reagents to silylated glutaconaldehyde 2 [(2E,4E)-5-trialkylsiloxy-2,4-pentadienal] as a five-carbon synthon. Application of the methodology to the synthesis of two dienamide natural products (pellitorine and sarmentine) are discussed.",

keywords = "CARBONYL-COMPOUNDS, ALDEHYDES",

author = "N LEWIS and MCKEN, {P W} and TAYLOR, {R J K}",

year = "1991",

month = dec,

language = "English",

pages = "898--900",

journal = "Synlett",

issn = "1437-2096",

publisher = "Georg Thieme Verlag",

number = "12",

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AU - LEWIS, N

AU - MCKEN, P W

AU - TAYLOR, R J K

PY - 1991/12

Y1 - 1991/12

N2 - A new procedure for the preparation of 2E,4E-dienals 4 is described based on the addition of organometallic reagents to silylated glutaconaldehyde 2 [(2E,4E)-5-trialkylsiloxy-2,4-pentadienal] as a five-carbon synthon. Application of the methodology to the synthesis of two dienamide natural products (pellitorine and sarmentine) are discussed.

AB - A new procedure for the preparation of 2E,4E-dienals 4 is described based on the addition of organometallic reagents to silylated glutaconaldehyde 2 [(2E,4E)-5-trialkylsiloxy-2,4-pentadienal] as a five-carbon synthon. Application of the methodology to the synthesis of two dienamide natural products (pellitorine and sarmentine) are discussed.

KW - CARBONYL-COMPOUNDS

KW - ALDEHYDES

M3 - Comment/debate

SN - 1437-2096

SP - 898

EP - 900

JO - Synlett

JF - Synlett

IS - 12

ER -