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A photolabile 'traceless' linker for solid-phase organic synthesis

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Publication details

JournalTetrahedron Letters
DatePublished - 18 Nov 2000
Issue number47
Volume41
Number of pages4
Pages (from-to)9181-9184
Original languageEnglish

Abstract

A photolabile linker based on a thiohydroxamic acid has been shown to be efficient 'traceless' linker, revealing an aliphatic CH bond on photolysis at 350 nm. Methods for the synthesis, loading and phtolytic cleavage of the linker are described. (C) 2000 Elsevier Science Ltd.

    Research areas

  • LINKING, CLEAVAGE

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