A radical approach to debenzylation of amides

S R Baker, A F Parsons, M Wilson

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The deprotection of N-benzylamides can be achieved under neutral conditions by reaction with N-bromosuccinimide in boiling chlorobenzene or ethyl acetate. Good to excellent yields are obtained using either acyclic or cyclic amides. (C) 1997 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)331-332
Number of pages2
JournalTetrahedron Letters
Issue number3-4
Publication statusPublished - 15 Jan 1998

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