A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2 '-deoxyadenosine affords a novel class of fluorescent analogues

T.E. Storr; J.A. Strohmeier; C.G. Baumann; I.J.S. Fairlamb

doi:10.1039/c0cc02043e

A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2 '-deoxyadenosine affords a novel class of fluorescent analogues

T.E. Storr, J.A. Strohmeier, C.G. Baumann, I.J.S. Fairlamb

Research output: Contribution to journal › Article › peer-review

Abstract

Novel rigid 8-biaryl-2'-deoxyadenosines with tuneable fluorescent properties can be accessed by an efficient sequential catalytic Pd-0-coupling approach.

Original language	English
Pages (from-to)	6470-6472
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	35
DOIs	https://doi.org/10.1039/c0cc02043e
Publication status	Published - 21 Sept 2010

Bibliographical note

Keywords

NUCLEOSIDE TRIPHOSPHATES
POLYMERASE INCORPORATION
OLIGONUCLEOTIDE PROBES
BASE ANALOGS
DNA
PURINE
2'-DEOXYURIDINE
CONSTRUCTION
DERIVATIVES
GUANOSINE

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title = "A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2 '-deoxyadenosine affords a novel class of fluorescent analogues",

abstract = "Novel rigid 8-biaryl-2'-deoxyadenosines with tuneable fluorescent properties can be accessed by an efficient sequential catalytic Pd-0-coupling approach.",

keywords = "NUCLEOSIDE TRIPHOSPHATES, POLYMERASE INCORPORATION, OLIGONUCLEOTIDE PROBES, BASE ANALOGS, DNA, PURINE, 2'-DEOXYURIDINE, CONSTRUCTION, DERIVATIVES, GUANOSINE",

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AU - Storr, T.E.

AU - Strohmeier, J.A.

AU - Baumann, C.G.

AU - Fairlamb, I.J.S.

PY - 2010/9/21

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KW - POLYMERASE INCORPORATION

KW - OLIGONUCLEOTIDE PROBES

KW - BASE ANALOGS

KW - DNA

KW - PURINE

KW - 2'-DEOXYURIDINE

KW - CONSTRUCTION

KW - DERIVATIVES

KW - GUANOSINE

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JO - Chemical Communications

JF - Chemical Communications

IS - 35

ER -

A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2 '-deoxyadenosine affords a novel class of fluorescent analogues

Abstract

Bibliographical note

Keywords

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