The York Research Database

Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes

Bell, A. S., Yu, Z., Hutton, J. A., Wright, M. H., Brannigan, J. A., Paape, D., Roberts, S. M., Sutherell, C. L., Ritzefeld, M., Wilkinson, A. J., Smith, D. F., Leatherbarrow, R. J. & Tate, E. W., 23 Jul 2020

Article in JOURNAL OF MEDICINAL CHEMISTRY

Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile

Whittingham, J. L., Hanai, S., Brannigan, J. A., Ferreira, W. T., Dodson, E. J., Turkenburg, J. P., Cartwright, J., Cutting, S. M. & Wilkinson, A. J., 1 Jun 2020

Article in Acta crystallographica. Section F, Structural biology communications

Water networks can determine the affinity of ligand binding to proteins

Darby, J. F., Hopkins, A., Hubbard, R. E., Roberts, S. M., Shimizu, S., Brannigan, J. A., Turkenburg, J., Thomas, G. H. & Fischer, M., 9 Oct 2019

Article in Journal of the American Chemical Society

Site-selective C-C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations

Spears, R. J., Brabham, R. L., Budhadev, D., Keenan, T., McKenna, S. E., Walton, J., Brannigan, J. A., Brzozowski, A. M., Wilkinson, A. J., Plevin, M. J. & Fascione, M. A., 7 Jul 2018

Article in Chemical Science

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus

Mousnier, A., Bell, A. S., Swieboda, D. P., Morales-Sanfrutos, J., Pérez-Dorado, I., Brannigan, J. A., Newman, J., Ritzefeld, M., Hutton, J. A., Guedán, A., Asfor, A. S., Robinson, S. W., Hopkins-Navratilova, I., Wilkinson, A. J., Johnston, S. L., Leatherbarrow, R. J., Tuthill, T. J., Solari, R. & Tate, E. W., 1 Jun 2018

Article in Nature Chemistry

The crystal structure of NusB from Mycobacterium tuberculosis

Gopal, B., Haire, L. F., Cox, R. A., Colston, M. J., Major, S., Brannigan, J. A., Smerdon, S. J. & Dodson, G., Jun 2000

Article in Nature Structural Biology

Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members

Suresh, C. G., Pundle, A. V., SivaRaman, H., Rao, K. N., Brannigan, J. A., McVey, C. E., Verma, C. S., Dauter, Z., Dodson, E. J. & Dodson, G. G., May 1999

Article in Nature Structural Biology

Illuminating crystallography

Wilson, K. S., Aug 1998

Literature review in Nature Structural Biology

The X-ray structure of a cobalamin biosynthetic enzyme, cobalt-precorrin-4 methyltransferase

Schubert, H. L., Wilson, K. S., Raux, E., Woodcock, S. C. & Warren, M. J., Jul 1998

Article in Nature Structural Biology