By the same authors

From the same journal

A simplified route to the (R)-Garner aldehyde and (S)-vinyl glycinol

Research output: Contribution to journalArticle



Publication details

DatePublished - Dec 1998
Issue number12
Number of pages3
Pages (from-to)1707-1709
Original languageEnglish


An improved procedure for the conversion of D-serine into tert-butyl (R)-4-formyl-2,2-dimethyloxazolidine-3-caboxylate [the (R)-Garner aldehyde] is described which can be carried out in four operationally simple steps in 88% overall yield. Elaboration of this aldehyde to vinyl glycinol is also described.

    Research areas

  • serine, garner aldehyde, Weinreb amide, vinyl glycinol, amino acids, ALPHA-AMINO-ACIDS, L-SERINE, DIASTEREOSELECTIVE SYNTHESIS, DERIVATIVES, CONVERSION, EQUIVALENT, ANALOGS

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