A tale of two bioconjugations: pH controlled divergent reactivity of protein a-oxo aldehydes in competing a-oxo-Mannich and catalyst-free aldol ligations

Tessa Keenan, Richard J Spears, Saeed Akkad, Clare S Mahon, Natasha E Hatton, Julia Walton, Amanda Noble, Nicholas D Yates, Christoph G Baumann, Alison Parkin, Nathalie Signoret, Martin A Fascione

Research output: Contribution to journal › Article › peer-review

1 results

Finished

Modify-Catch-Release-Repeat: Reversible bioconjugations for controlled release of small molecules from antibodies and their fragments
Fascione, M. A. (Principal investigator), Davies, G. J. (Co-investigator), Southgate, J. (Co-investigator) & Ungar, D. (Co-investigator)
EPSRC
1/01/19 → 31/03/23
Project: Research project (funded) › Research