The CheckMAP tool provides a list of signalling questions to consider when checking and appraising an individual participant data (IPD) meta-analysis project, and answers of ‘yes’ to questions are indicative of higher quality. A summary of the CheckMAP assessment provides a useful overview of the quality of a particular IPD meta-analysis project. A key component of appraising an IPD meta-analysis project evaluating the treatment effects is determining whether it has been done as part of a systematic review. As for conventional systematic reviews, IPD meta-analysis projects require that explicit objectives and eligibility criteria are pre-specified to minimise bias in the selection of trials, participants and outcomes for inclusion. Clear objectives and eligibility criteria should have been backed up by a systematic and comprehensive search that seeks to identify all relevant trials. CheckMAP checklist and guidance on critical appraisal has focused on IPD meta-analyses that examine the efficacy of one particular treatment compared to a control.
|Title of host publication
|Individual Participant Data Meta-Analysis
|Subtitle of host publication
|a Handbook for Healthcare Research
|Wiley-Blackwell Publishing Ltd
|Number of pages
|Published - 22 Apr 2021
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