By the same authors

From the same journal

A UK Consensus Group on management of glucocorticoid-induced osteoporosis: an update

Research output: Contribution to journalLiterature review

Author(s)

  • R Eastell
  • D M Reid
  • J Compston
  • C Cooper
  • I Fogelman
  • R M Francis
  • D J Hosking
  • D W Purdie
  • S H Ralston
  • J Reeve
  • R G G Russell
  • J C Stevenson
  • D J Torgerson

Department/unit(s)

Publication details

JournalJournal of general internal medicine
DatePublished - Oct 1998
Issue number4
Volume244
Number of pages22
Pages (from-to)271-292
Original languageEnglish

Abstract

In the UK, over 250 000 patients take continuous oral glucocorticoids (GCs), yet no more than 14% receive any therapy to prevent bone loss, a major complication of GC treatment. Bone loss is rapid, particularly in the first year, and fracture risk may double. This review, based wherever possible on clinical evidence, aims to provide easy-to-use guidance with wide applicability. A treatment algorithm is presented for adults receiving GC doses of 7.5 mg day(-1) or more for 6 months or more. General measures, e.g, alternative GCs and routes of administration, and therapeutic interventions, e.g, cyclical etidronate and hormone replacement, are recommended.

    Research areas

  • adults, children, high-dose glucocorticoids, management and osteoporosis, CORTICOSTEROID-INDUCED OSTEOPOROSIS, BONE-MINERAL DENSITY, LOW-DOSE CORTICOSTEROIDS, INTESTINAL CALCIUM-ABSORPTION, CARDIAC TRANSPLANT RECIPIENTS, STEROID-INDUCED OSTEOPOROSIS, RHEUMATOID-ARTHRITIS, SERUM OSTEOCALCIN, DOUBLE-BLIND, VITAMIN-D

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