By the same authors

From the same journal

Adverse reactions, psychological factors, and their effect on donor retention in men and women

Research output: Contribution to journalArticlepeer-review



Publication details

JournalTransfusion Medicine
DatePublished - Sep 2012
Issue number9
Number of pages9
Pages (from-to)1871-9
Original languageEnglish


BACKGROUND: This study investigates the effect of a vasovagal reaction (VVR) or needle reaction (NR) on the risk of stopping as a blood donor, taking into account variables from the Theory of Planned Behavior (TPB). Is stopping risk solely related to the adverse reaction itself, or do the TPB variables play a role as well? Emphasis is placed on possible sex differences.

STUDY DESIGN AND METHODS: TPB variables were assessed within 12,051 whole blood donors. Also, donors reported the occurrence of adverse reactions during or after their last donation. Blood bank records were used to determine whether donors stopped donating within the next 2 years. Logistic regression analyses were performed to estimate the effect of self-reported adverse reactions on stopping risk, adjusting for the TPB variables. Analyses were performed separately for both sexes.

RESULTS: Men have a lower odds of reporting a NR or a VVR than women (odds ratio [OR] 0.34, 95% confidence interval [CI], 0.28-0.43; and OR 0.26, 95% CI 0.19-0.36, for NR and VVR, respectively). For both sexes, only a VVR was associated with stopping risk, which is higher in men (men, OR 3.95, 95% CI 2.19-7.11; women, OR 1.78, 95% CI 1.35-2.35). After adjusting for the TPB variables both ORs declined (men, OR 3.38, 95% CI 1.86-6.15; women, OR 1.58, 95% CI 1.17-2.14). Also, self-efficacy and affective attitude are negatively associated with adverse reactions.

CONCLUSION: Female donors report more VVRs than male donors, but male donors have a higher stopping risk after a VVR than female donors. Coping differences and possible reporting tendencies might play a role. For donor retention purposes, prevention and coping techniques should take sex differences into account.

    Research areas

  • Adult, Attitude to Health, Blood Donors/psychology, Blood Specimen Collection/adverse effects, Female, Humans, Male, Middle Aged, Models, Biological, Needlestick Injuries/epidemiology, Patient Selection, Registries/statistics & numerical data, Self Efficacy, Sex Characteristics, Syncope, Vasovagal/epidemiology

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations