The York Research Database

Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action

Bule, P., Chuzel, L., Blagova, E., Wu, L., Gray, M. A., Henrissat, B., Rapp, E., Bertozzi, C. R., Taron, C. H. & Davies, G. J., 23 Sep 2019, (Accepted/In press)

Article in Nature Communications

α-D-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease

Artola, M., Hedberg, C., Rowland, R. J., Raich, L., Kytidou, K., Wu, L., Schaafa, A., Ferraz, M. J., van der Marel, G. A., Codée, J. D. C., Rovira, C., Aerts, J. M. F. G., Davies, G. J. & Overkleeft, H. S., 20 Aug 2019

Article in Chemical Science

Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes

Schröder, S. P., De Boer, C., McGregor, N. G. S., Rowland, R. J., Moroz, O., Blagova, E., Reijngoud, J., Arentshorst, M., Osborn, D., Morant, M. D., Abbate, E., Stringer, M. A., Krogh, K. B. R. M., Raich, L., Rovira, C., Berrin, J. G., Van Wezel, G. P., Ram, A. F. J., Florea, B. I., Van Der Marel, G. A. & 5 othersCodée, J. D. C., Wilson, K. S., Wu, L., Davies, G. J. & Overkleeft, H. S., 26 Jun 2019

Article in ACS Central Science

Synthetic and crystallographic insight into exploiting sp2‐hybridization in the development of α‐L‐fucosidase inhibitors

Coyle, T., Wu, L., Debowski, A., Davies, G. & Stubbs, K. A., 21 Jan 2019

Article in Chembiochem

Synthesis of chiral amines using redox biocatalysis

Grogan, G., 1 Apr 2018

Review article in Current Opinion in Chemical Biology

Imine reductases (IREDs)

Mangas-Sanchez, J., France, S. P., Montgomery, S. L., Aleku, G. A., Man, H., Sharma, M., Ramsden, J. I., Grogan, G. & Turner, N. J., Apr 2017

Article in Current Opinion in Chemical Biology

On the catalytic mechanisms of lytic polysaccharide monooxygenases

Walton, P. H. & Davies, G. J., Apr 2016

Review article in Current Opinion in Chemical Biology

Lignocellulose degradation mechanisms across the Tree of Life

Cragg, S. M., Beckham, G. T., Bruce, N. C., Bugg, T. D. H., Distel, D. L., Dupree, P., Etxabe, A. G., Goodell, B. S., Jellison, J., McGeehan, J. E., McQueen-Mason, S. J., Schnorr, K., Walton, P. H., Watts, J. E. M. & Zimmer, M., Dec 2015

Review article in Current Opinion in Chemical Biology