The York Research Database

Manno- epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors

Armstrong, Z., Kuo, C. L., Lahav, D., Liu, B., Johnson, R., Beenakker, T. J. M., De Boer, C., Wong, C. S., Van Rijssel, E. R., Debets, M. F., Florea, B. I., Hissink, C., Boot, R. G., Geurink, P. P., Ovaa, H., Van Der Stelt, M., Van Der Marel, G. M., Codée, J. D. C., Aerts, J. M. F. G., Wu, L. & 2 others, Overkleeft, H. S. & Davies, G. J., 29 Jul 2020

Article in Journal of the American Chemical Society

Structural insights into pixatimod (PG545) inhibition of heparanase, a key enzyme in cancer and viral infections

Chhabra, M., Wilson, J. C., Wu, L., Davies, G. J., Gandhi, N. S. & Ferro, V., 4 Jan 2022, (Accepted/In press)

Article in Chemistry : A European Journal

Synthesis of Broad-Specificity Activity-Based Probes for Exo-β-Mannosidases

McGregor, N. G. S., Kuo, C-L., Beenakker, T. J. M., Wong, C-S., Offen, W. A., Armstrong, Z., Florea, B. I., Codée, J. D. C., Overkleeft, H. S., Aerts, J. M. F. G. & Davies, G. J., 23 Dec 2021, (E-pub ahead of print)

Article in Organic & biomolecular chemistry

Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents

Rowland, R. J., Chen, Y., Breen, I., Wu, L., Offen, W. A., Beenakker, T., Su, Q., van den Nieuwendijk, A. M. C. H., Aerts, J. M. F. G., Artola, M., Overkleeft, H. S. & Davies, G. J., 29 Oct 2021, (E-pub ahead of print)

Article in Chemistry : A European Journal

Activity-based protein profiling of retaining α-amylases in complex biological samples

Chen, Y., Armstrong, Z., Artola, M., Florea, B. I., Kuo, C-L., de Boer, C., Rasmussen, M. S., Hachem, M. A., van der Marel, G. A., Codée, J. D. C., Aerts, J. M. F. G., Davies, G. J. & Overkleeft, H. S., 26 Jan 2021, (E-pub ahead of print)

Article in Journal of the American Chemical Society

How Synthetic Biology Can Help Bioremediation

Rylott, L. & Bruce, N. C., 14 Aug 2020, (E-pub ahead of print)

Article in Current Opinion in Chemical Biology

Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)–processing enzymes

King, D., Males, A., Davies, G. J. & Vocadlo, D., 1 Dec 2019

Article in Current Opinion in Chemical Biology

Synthesis of chiral amines using redox biocatalysis

Grogan, G., 1 Apr 2018

Review article in Current Opinion in Chemical Biology

Imine reductases (IREDs)

Mangas-Sanchez, J., France, S. P., Montgomery, S. L., Aleku, G. A., Man, H., Sharma, M., Ramsden, J. I., Grogan, G. & Turner, N. J., Apr 2017

Article in Current Opinion in Chemical Biology