Analysis of crystallization data the Protein Data Bank

Jobie Samuel Kirkwood, David Hargreaves, Simon O'Keefe, Julie C. Wilson

Research output: Contribution to journalArticlepeer-review


The Protein Data Bank (PDB) is the largest available repository of solved
protein structures and contains a wealth of information on successful
crystallization. Many centres have used their own experimental data to draw
conclusions about proteins and the conditions in which they crystallize. Here,
data from the PDB were used to reanalyse some of these results. The most
successful crystallization reagents were identified, the link between solution pH
and the isoelectric point of the protein was investigated and the possibility of
predicting whether a protein will crystallize was explored.
Original languageEnglish
Pages (from-to)1228-1234
Number of pages7
JournalActa Crystallographica Section F: Structural Biology and Crystallization Communications
Issue number10
Publication statusPublished - Oct 2015

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