Analysis of crystallization data the Protein Data Bank

Jobie Samuel Kirkwood; David Hargreaves; Simon O'Keefe; Julie C. Wilson

doi:10.1107/S2053230X15014892

Analysis of crystallization data the Protein Data Bank

Jobie Samuel Kirkwood, David Hargreaves, Simon O'Keefe, Julie C. Wilson

Research output: Contribution to journal › Article › peer-review

Abstract

The Protein Data Bank (PDB) is the largest available repository of solved
protein structures and contains a wealth of information on successful
crystallization. Many centres have used their own experimental data to draw
conclusions about proteins and the conditions in which they crystallize. Here,
data from the PDB were used to reanalyse some of these results. The most
successful crystallization reagents were identified, the link between solution pH
and the isoelectric point of the protein was investigated and the possibility of
predicting whether a protein will crystallize was explored.

Original language	English
Pages (from-to)	1228-1234
Number of pages	7
Journal	Acta Crystallographica Section F: Structural Biology and Crystallization Communications
Volume	71
Issue number	10
DOIs	https://doi.org/10.1107/S2053230X15014892
Publication status	Published - Oct 2015

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10.1107/S2053230X15014892

JobieAnalysysofDataInPDB
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Cite this

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