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Analysis of crystallization data the Protein Data Bank

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JournalActa Crystallographica Section F: Structural Biology and Crystallization Communications
DatePublished - Oct 2015
Issue number10
Volume71
Number of pages7
Pages (from-to)1228-1234
Original languageEnglish

Abstract

The Protein Data Bank (PDB) is the largest available repository of solved
protein structures and contains a wealth of information on successful
crystallization. Many centres have used their own experimental data to draw
conclusions about proteins and the conditions in which they crystallize. Here,
data from the PDB were used to reanalyse some of these results. The most
successful crystallization reagents were identified, the link between solution pH
and the isoelectric point of the protein was investigated and the possibility of
predicting whether a protein will crystallize was explored.

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