Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Marta Pereira Verdugo; Victoria E Mullin; Amelie Scheu; Valeria Mattiangeli; Kevin G Daly; Pierpaolo Maisano Delser; Andrew J Hare; Joachim Burger; Matthew J Collins; Ron Kehati; Paula Hesse; Deirdre Fulton; Eberhard W Sauer; Fatemeh A Mohaseb; Hossein Davoudi; Roya Khazaeli; Johanna Lhuillier; Claude Rapin; Saeed Ebrahimi; Mutalib Khasanov; S M Farhad Vahidi; David E MacHugh; Okan Ertuğrul; Chaido Koukouli-Chrysanthaki; Adamantios Sampson; George Kazantzis; Ioannis Kontopoulos; Jelena Bulatovic; Ivana Stojanović; Abdesalam Mikdad; Norbert Benecke; Jörg Linstädter; Mikhail Sablin; Robin Bendrey; Lionel Gourichon; Benjamin S Arbuckle; Marjan Mashkour; David Orton; Liora Kolska Horwitz; Matthew D Teasdale; Daniel G Bradley

doi:10.1126/science.aav1002

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Marta Pereira Verdugo, Victoria E Mullin, Amelie Scheu, Valeria Mattiangeli, Kevin G Daly, Pierpaolo Maisano Delser, Andrew J Hare, Joachim Burger, Matthew J Collins, Ron Kehati, Paula Hesse, Deirdre Fulton, Eberhard W Sauer, Fatemeh A Mohaseb, Hossein Davoudi, Roya Khazaeli, Johanna Lhuillier, Claude Rapin, Saeed Ebrahimi, Mutalib KhasanovS M Farhad Vahidi, David E MacHugh, Okan Ertuğrul, Chaido Koukouli-Chrysanthaki, Adamantios Sampson, George Kazantzis, Ioannis Kontopoulos, Jelena Bulatovic, Ivana Stojanović, Abdesalam Mikdad, Norbert Benecke, Jörg Linstädter, Mikhail Sablin, Robin Bendrey, Lionel Gourichon, Benjamin S Arbuckle, Marjan Mashkour, David Orton, Liora Kolska Horwitz, Matthew D Teasdale, Daniel G Bradley

Archaeology

Research output: Contribution to journal › Article › peer-review

Abstract

Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.

Original language	English
Pages (from-to)	173-176
Number of pages	4
Journal	Science
Volume	365
Issue number	6449
DOIs	https://doi.org/10.1126/science.aav1002
Publication status	Published - 12 Jul 2019

Bibliographical note

© 2019 American Association for the Advancement of Science. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

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Cite this

Verdugo, M. P., Mullin, V. E., Scheu, A., Mattiangeli, V., Daly, K. G., Maisano Delser, P., Hare, A. J., Burger, J., Collins, M. J., Kehati, R., Hesse, P., Fulton, D., Sauer, E. W., Mohaseb, F. A., Davoudi, H., Khazaeli, R., Lhuillier, J., Rapin, C., Ebrahimi, S., ... Bradley, D. G. (2019). Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent. Science, 365(6449), 173-176. https://doi.org/10.1126/science.aav1002

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abstract = "Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.",

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Verdugo, MP, Mullin, VE, Scheu, A, Mattiangeli, V, Daly, KG, Maisano Delser, P, Hare, AJ, Burger, J, Collins, MJ, Kehati, R, Hesse, P, Fulton, D, Sauer, EW, Mohaseb, FA, Davoudi, H, Khazaeli, R, Lhuillier, J, Rapin, C, Ebrahimi, S, Khasanov, M, Vahidi, SMF, MacHugh, DE, Ertuğrul, O, Koukouli-Chrysanthaki, C, Sampson, A, Kazantzis, G, Kontopoulos, I, Bulatovic, J, Stojanović, I, Mikdad, A, Benecke, N, Linstädter, J, Sablin, M, Bendrey, R, Gourichon, L, Arbuckle, BS, Mashkour, M, Orton, D, Horwitz, LK, Teasdale, MD & Bradley, DG 2019, 'Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent', Science, vol. 365, no. 6449, pp. 173-176. https://doi.org/10.1126/science.aav1002

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AU - Scheu, Amelie

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AU - Daly, Kevin G

AU - Maisano Delser, Pierpaolo

AU - Hare, Andrew J

AU - Burger, Joachim

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AU - Kehati, Ron

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AU - Davoudi, Hossein

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AU - Ebrahimi, Saeed

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AU - Vahidi, S M Farhad

AU - MacHugh, David E

AU - Ertuğrul, Okan

AU - Koukouli-Chrysanthaki, Chaido

AU - Sampson, Adamantios

AU - Kazantzis, George

AU - Kontopoulos, Ioannis

AU - Bulatovic, Jelena

AU - Stojanović, Ivana

AU - Mikdad, Abdesalam

AU - Benecke, Norbert

AU - Linstädter, Jörg

AU - Sablin, Mikhail

AU - Bendrey, Robin

AU - Gourichon, Lionel

AU - Arbuckle, Benjamin S

AU - Mashkour, Marjan

AU - Orton, David

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N2 - Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.

AB - Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.

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DO - 10.1126/science.aav1002

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JF - Science

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