Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Kevin Daly; Pierpaolo Maisano Delser; Victoria Mullin; Amelie  Scheu; Valeria Mattiangeli; Matthew David Teasdale; Andrew Hare; Joachim Burger; Marta Pereira Verdugo; Matthew James Collins; Ron Kehati; Cevdet Merih Erek; Guy Bar-Oz; François Pompanon; Tristan Cumer; Canan Çakirlar; Azadeh Fatemah Mohaseb; Delphine Decruyenaere; Hossein Davoudi; Özlem Çevik; Gary Rollefson; Jean-Denis Vigne; Khazaeli Roya; Homa Fathi; Sanaz Beizaee Doost; Roghayeh Rahimi Sorkhani; Ali Akbar Vahdati; Eberhard W. Sauer; Hossein Azizi Kharanaghi; Sepideh Maziar; Boris Gasparian; Ron Pinhasi; Louise Martin; David Clive Orton; Benjamin S. Arbuckle; Norbert  Benecke; Andrea Manica; Liora Kolska Horwitz; Marjan  Mashkour; Daniel Bradley

doi:10.1126/science.aas9411

Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Kevin Daly, Pierpaolo Maisano Delser, Victoria Mullin, Amelie Scheu, Valeria Mattiangeli, Matthew David Teasdale, Andrew Hare, Joachim Burger, Marta Pereira Verdugo, Matthew James Collins, Ron Kehati, Cevdet Merih Erek, Guy Bar-Oz, François Pompanon, Tristan Cumer, Canan Çakirlar, Azadeh Fatemah Mohaseb, Delphine Decruyenaere, Hossein Davoudi, Özlem ÇevikGary Rollefson, Jean-Denis Vigne, Khazaeli Roya, Homa Fathi, Sanaz Beizaee Doost, Roghayeh Rahimi Sorkhani, Ali Akbar Vahdati, Eberhard W. Sauer, Hossein Azizi Kharanaghi, Sepideh Maziar, Boris Gasparian, Ron Pinhasi, Louise Martin, David Clive Orton, Benjamin S. Arbuckle, Norbert Benecke, Andrea Manica, Liora Kolska Horwitz, Marjan Mashkour, Daniel Bradley

Archaeology

Research output: Contribution to journal › Article › peer-review

Abstract

Current genetic data are equivocal as to whether goat domestication occurred multiple times
or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage), from Palaeolithic through to Medieval contexts throughout the Near East. Our results demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process, resulting in genetically and geographically-distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa and Europe. We also detect early selection for pigmentation, stature, reproduction, milking and response to dietary change, providing 8,000 year old evidence for human agency in moulding genome variation within a partner species.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Science
Volume	361
Issue number	6397
DOIs	https://doi.org/10.1126/science.aas9411
Publication status	Published - 6 Jul 2018

Bibliographical note

© 2018 American Association for the Advancement of Science. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

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Daly, K., Maisano Delser, P., Mullin, V., Scheu, A., Mattiangeli, V., Teasdale, M. D., Hare, A., Burger, J., Pereira Verdugo, M., Collins, M. J., Kehati, R., Erek, C. M., Bar-Oz, G., Pompanon, F., Cumer, T., Çakirlar, C., Mohaseb, A. F., Decruyenaere, D., Davoudi, H., ... Bradley, D. (2018). Ancient goat genomes reveal mosaic domestication in the Fertile Crescent. Science, 361(6397), 85-88. https://doi.org/10.1126/science.aas9411

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title = "Ancient goat genomes reveal mosaic domestication in the Fertile Crescent",

abstract = "Current genetic data are equivocal as to whether goat domestication occurred multiple timesor was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage), from Palaeolithic through to Medieval contexts throughout the Near East. Our results demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process, resulting in genetically and geographically-distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa and Europe. We also detect early selection for pigmentation, stature, reproduction, milking and response to dietary change, providing 8,000 year old evidence for human agency in moulding genome variation within a partner species.",

author = "Kevin Daly and {Maisano Delser}, Pierpaolo and Victoria Mullin and Amelie Scheu and Valeria Mattiangeli and Teasdale, {Matthew David} and Andrew Hare and Joachim Burger and {Pereira Verdugo}, Marta and Collins, {Matthew James} and Ron Kehati and Erek, {Cevdet Merih} and Guy Bar-Oz and Fran{\c c}ois Pompanon and Tristan Cumer and Canan {\c C}akirlar and Mohaseb, {Azadeh Fatemah} and Delphine Decruyenaere and Hossein Davoudi and {\"O}zlem {\c C}evik and Gary Rollefson and Jean-Denis Vigne and Khazaeli Roya and Homa Fathi and {Beizaee Doost}, Sanaz and {Rahimi Sorkhani}, Roghayeh and Vahdati, {Ali Akbar} and Sauer, {Eberhard W.} and {Azizi Kharanaghi}, Hossein and Sepideh Maziar and Boris Gasparian and Ron Pinhasi and Louise Martin and Orton, {David Clive} and Arbuckle, {Benjamin S.} and Norbert Benecke and Andrea Manica and {Kolska Horwitz}, Liora and Marjan Mashkour and Daniel Bradley",

note = "{\textcopyright} 2018 American Association for the Advancement of Science. This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details.",

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doi = "10.1126/science.aas9411",

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Daly, K, Maisano Delser, P, Mullin, V, Scheu, A, Mattiangeli, V, Teasdale, MD, Hare, A, Burger, J, Pereira Verdugo, M, Collins, MJ, Kehati, R, Erek, CM, Bar-Oz, G, Pompanon, F, Cumer, T, Çakirlar, C, Mohaseb, AF, Decruyenaere, D, Davoudi, H, Çevik, Ö, Rollefson, G, Vigne, J-D, Roya, K, Fathi, H, Beizaee Doost, S, Rahimi Sorkhani, R, Vahdati, AA, Sauer, EW, Azizi Kharanaghi, H, Maziar, S, Gasparian, B, Pinhasi, R, Martin, L, Orton, DC, Arbuckle, BS, Benecke, N, Manica, A, Kolska Horwitz, L, Mashkour, M & Bradley, D 2018, 'Ancient goat genomes reveal mosaic domestication in the Fertile Crescent', Science, vol. 361, no. 6397, pp. 85-88. https://doi.org/10.1126/science.aas9411

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AU - Daly, Kevin

AU - Maisano Delser, Pierpaolo

AU - Mullin, Victoria

AU - Scheu, Amelie

AU - Mattiangeli, Valeria

AU - Teasdale, Matthew David

AU - Hare, Andrew

AU - Burger, Joachim

AU - Pereira Verdugo, Marta

AU - Collins, Matthew James

AU - Kehati, Ron

AU - Erek, Cevdet Merih

AU - Bar-Oz, Guy

AU - Pompanon, François

AU - Cumer, Tristan

AU - Çakirlar, Canan

AU - Mohaseb, Azadeh Fatemah

AU - Decruyenaere, Delphine

AU - Davoudi, Hossein

AU - Çevik, Özlem

AU - Rollefson, Gary

AU - Vigne, Jean-Denis

AU - Roya, Khazaeli

AU - Fathi, Homa

AU - Beizaee Doost, Sanaz

AU - Rahimi Sorkhani, Roghayeh

AU - Vahdati, Ali Akbar

AU - Sauer, Eberhard W.

AU - Azizi Kharanaghi, Hossein

AU - Maziar, Sepideh

AU - Gasparian, Boris

AU - Pinhasi, Ron

AU - Martin, Louise

AU - Orton, David Clive

AU - Arbuckle, Benjamin S.

AU - Benecke, Norbert

AU - Manica, Andrea

AU - Kolska Horwitz, Liora

AU - Mashkour, Marjan

AU - Bradley, Daniel

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N2 - Current genetic data are equivocal as to whether goat domestication occurred multiple timesor was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage), from Palaeolithic through to Medieval contexts throughout the Near East. Our results demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process, resulting in genetically and geographically-distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa and Europe. We also detect early selection for pigmentation, stature, reproduction, milking and response to dietary change, providing 8,000 year old evidence for human agency in moulding genome variation within a partner species.

AB - Current genetic data are equivocal as to whether goat domestication occurred multiple timesor was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage), from Palaeolithic through to Medieval contexts throughout the Near East. Our results demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process, resulting in genetically and geographically-distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa and Europe. We also detect early selection for pigmentation, stature, reproduction, milking and response to dietary change, providing 8,000 year old evidence for human agency in moulding genome variation within a partner species.

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U2 - 10.1126/science.aas9411

DO - 10.1126/science.aas9411

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VL - 361

SP - 85

EP - 88

JO - Science

JF - Science

IS - 6397

ER -

Ancient goat genomes reveal mosaic domestication in the Fertile Crescent

Abstract

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