The York Research Database
- » Research
- » York Research Database
- » Publications
- » Anti-cancer palladium complexes
Anti-cancer palladium complexes: a focus on PdX2L2, palladacycles and related complexes
Research output: Contribution to journal › Review article › peer-review
Published copy (DOI)
Author(s)
Department/unit(s)
Publication details
| Journal | Chemical Society Reviews |
|---|---|
| Date | Published - 11 Apr 2014 |
| Issue number | 13 |
| Volume | 43 |
| Number of pages | 27 |
| Pages (from-to) | 4751-4777 |
| Original language | English |
Abstract
Much success has been achieved with platinum-based chemotherapeutic agents, i.e. through interactions with DNA. The long-term application of Pt complexes is thwarted by issues, leading scientists to examine other metals such as palladium which could exhibit complementary modes of action (given emphasis wherever known). Over the last 10 years several research groups have focused on the application of an eclectic array of palladium complexes (of the type PdX2L2, palladacycles and related structures) as potential anti-cancer agents. This review therefore provides readers with an up to date account of the advances that have taken place over the past several decades.
- Palladium, Anti-cancer, Cancer, Cell lines, DRUG DISCOVERY
Research areas
Discover related content
Find related publications, people, projects, datasets and more using interactive charts.