By the same authors

From the same journal

APPLICATION OF ENZYMATIC BAEYER-VILLIGER OXIDATIONS OF 2-SUBSTITUTED CYCLOALKANONES TO THE TOTAL SYNTHESIS OF (R)-(+)-LIPOIC ACID

Research output: Contribution to journalArticle

Author(s)

  • B ADGER
  • M T BES
  • G GROGAN
  • R MCCAGUE
  • S PEDRAGOSAMOREAU
  • S M ROBERTS
  • R VILLA
  • P W H WAN
  • A J WILLETTS

Department/unit(s)

Publication details

JournalJOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
DatePublished - 7 Aug 1995
Issue number15
Number of pages2
Pages (from-to)1563-1564
Original languageEnglish

Abstract

Oxidation of ketones 1a-h using a monooxygenase from Pseudomonas putida NCIMB 10007 gave the lactones 2a-h in optically active form: lactone 2h was converted into (R)-(+)-lipoic acid 9.

    Research areas

  • ALPHA-LIPOIC ACID, R-(+)-ALPHA-LIPOIC ACID, (R)-(+)-ALPHA-LIPOIC ACID, ENANTIOSELECTIVE SYNTHESIS, QUANTITATIVE-ANALYSES, ENANTIOMERS

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