Are there specific translational challenges in regenerative medicine? Lessons from other fields

John Grant Gardner; Alex Faulkner; Aurelie Mahalatchimy; Andrew Joseph Webster

doi:10.2217/rme.15.50

Are there specific translational challenges in regenerative medicine? Lessons from other fields

John Grant Gardner, Alex Faulkner, Aurelie Mahalatchimy, Andrew Joseph Webster

Sociology

Research output: Contribution to journal › Article › peer-review

Abstract

There is concern that translation ‘from bench to bedside’ within regenerative medicine (RM) will fail to materialise, or will be dismally slow, due to various challenges arising from the highly novel and disruptive nature of RM. In this article, we provide a summary of these challenges, and we critically engage with the notion that such challenges are specific to RM. It is important, we argue, not to overstate the exceptional nature of RM, as valuable lessons can be learned from elsewhere in medicine. Using several examples of technology adoption, we suggest that emerging RM products and procedures will have to work hard to find or create an adoption space if translation into the clinic is to be successful.

Original language	English
Pages (from-to)	885-895
Number of pages	11
Journal	REGENERATIVE MEDICINE
Volume	10
Issue number	7
Early online date	9 Oct 2015
DOIs	https://doi.org/10.2217/rme.15.50
Publication status	Published - 13 Oct 2015

Bibliographical note

This is an author-produced version of a paper accepted for publication. Uploaded with permission of the publisher/copyright holder. Further copying may not be permitted; contact the publisher for details

Access to Document

10.2217/rme.15.50

Pre-print Are there specific translational challenges
This is an author-produced version of a paper accepted for publication. Uploaded with permission of the publisher/copyright holder. Further copying may not be permitted; contact the publisher for details
Submitted manuscript, 113 KB

http://www.futuremedicine.com/doi/full/10.2217/rme.15.50

Regenerative medicine and its development and implementation:
WEBSTER, A. J. (Principal investigator)
ECONOMIC AND SOCIAL RESEARCH COUNCIL (ESRC)
1/05/14 → 31/07/17
Project: Research project (funded) › Research

Cite this

@article{6ca0c454288a40fabe57f8ca62d36202,

title = "Are there specific translational challenges in regenerative medicine? Lessons from other fields",

abstract = "There is concern that translation {\textquoteleft}from bench to bedside{\textquoteright} within regenerative medicine (RM) will fail to materialise, or will be dismally slow, due to various challenges arising from the highly novel and disruptive nature of RM. In this article, we provide a summary of these challenges, and we critically engage with the notion that such challenges are specific to RM. It is important, we argue, not to overstate the exceptional nature of RM, as valuable lessons can be learned from elsewhere in medicine. Using several examples of technology adoption, we suggest that emerging RM products and procedures will have to work hard to find or create an adoption space if translation into the clinic is to be successful. ",

author = "Gardner, {John Grant} and Alex Faulkner and Aurelie Mahalatchimy and Webster, {Andrew Joseph}",

note = "This is an author-produced version of a paper accepted for publication. Uploaded with permission of the publisher/copyright holder. Further copying may not be permitted; contact the publisher for details",

year = "2015",

month = oct,

day = "13",

doi = "10.2217/rme.15.50",

language = "English",

volume = "10",

pages = "885--895",

journal = "REGENERATIVE MEDICINE",

issn = "1746-0751",

publisher = "Taylor and Francis Ltd.",

number = "7",

}

TY - JOUR

T1 - Are there specific translational challenges in regenerative medicine? Lessons from other fields

AU - Gardner, John Grant

AU - Faulkner, Alex

AU - Mahalatchimy, Aurelie

AU - Webster, Andrew Joseph

N1 - This is an author-produced version of a paper accepted for publication. Uploaded with permission of the publisher/copyright holder. Further copying may not be permitted; contact the publisher for details

PY - 2015/10/13

Y1 - 2015/10/13

N2 - There is concern that translation ‘from bench to bedside’ within regenerative medicine (RM) will fail to materialise, or will be dismally slow, due to various challenges arising from the highly novel and disruptive nature of RM. In this article, we provide a summary of these challenges, and we critically engage with the notion that such challenges are specific to RM. It is important, we argue, not to overstate the exceptional nature of RM, as valuable lessons can be learned from elsewhere in medicine. Using several examples of technology adoption, we suggest that emerging RM products and procedures will have to work hard to find or create an adoption space if translation into the clinic is to be successful.

AB - There is concern that translation ‘from bench to bedside’ within regenerative medicine (RM) will fail to materialise, or will be dismally slow, due to various challenges arising from the highly novel and disruptive nature of RM. In this article, we provide a summary of these challenges, and we critically engage with the notion that such challenges are specific to RM. It is important, we argue, not to overstate the exceptional nature of RM, as valuable lessons can be learned from elsewhere in medicine. Using several examples of technology adoption, we suggest that emerging RM products and procedures will have to work hard to find or create an adoption space if translation into the clinic is to be successful.

U2 - 10.2217/rme.15.50

DO - 10.2217/rme.15.50

M3 - Article

SN - 1746-0751

VL - 10

SP - 885

EP - 895

JO - REGENERATIVE MEDICINE

JF - REGENERATIVE MEDICINE

IS - 7

ER -

Are there specific translational challenges in regenerative medicine? Lessons from other fields

Abstract

Bibliographical note

Access to Document

Projects

Regenerative medicine and its development and implementation:

Cite this