Artificial metalloenzymes: the powerful alliance between protein scaffolds and organometallic catalysts

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In recent years, substantial advances have been made in the development of artificial metalloenzymes. These hybrid bioinorganic catalysts have seen their selectivity improved through techniques including site-directed and site-saturation mutagenesis and directed evolution. Their scope has been expanded by the introduction of various abiological metal catalysts, the development of new anchoring strategies and new designs to enhance their reusability by conceiving modular and reversible assemblies. This review highlights a selection of the most significant advances made in the last two years and their contribution to the development of a more sustainable chemistry
Original languageEnglish
Article number100420
Number of pages7
JournalCurrent Opinion in Green and Sustainable Chemistry
Early online date1 Dec 2020
Publication statusPublished - 1 Apr 2021

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