As nice as π: aromatic reactions activated by π‐coordination to transition metals

Luke  Williams; Yunas  Bhonoah; Luke Alexander Wilkinson; James Walton

doi:10.1002/chem.202004621

As nice as π: aromatic reactions activated by π‐coordination to transition metals

Luke Williams, Yunas Bhonoah, Luke Alexander Wilkinson, James Walton

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

π‐Coordination of aromatic molecules to metals dramatically alters their reactivity. For example, coordinated carbons become more electrophilic and C‐H bonds of coordinated rings become more acidic. For many years, this change in reactivity has been used to trigger reactions that would not take place for uncoordinated arenes, however, there has been a recent resurgence in use of this technique, in part due to the development of catalytic reactions in which π‐coordination is transient. In this minireview, we describe the key reaction chemistry of arenes coordinated to a range of transition metals, including stereoselective reactions and industrially relevant syntheses. We also summarize outstanding examples of catalytic processes. Finally, we give perspectives on the future direction of the field, with respect to both reactions that are stoichiometric in activating metals and those employing catalytic metal

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	Chemistry : A European Journal
Early online date	7 Jan 2021
DOIs	https://doi.org/10.1002/chem.202004621
Publication status	E-pub ahead of print - 7 Jan 2021

Bibliographical note

 2020 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH

Access to Document

10.1002/chem.202004621Licence: CC BY

chem.202004621
 2020 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH
Final published version, 3.09 MBLicence: CC BY

Cite this

@article{78e16cdd5398499b9e1194c20eb65003,

title = "As nice as π: aromatic reactions activated by π‐coordination to transition metals",

abstract = "π‐Coordination of aromatic molecules to metals dramatically alters their reactivity. For example, coordinated carbons become more electrophilic and C‐H bonds of coordinated rings become more acidic. For many years, this change in reactivity has been used to trigger reactions that would not take place for uncoordinated arenes, however, there has been a recent resurgence in use of this technique, in part due to the development of catalytic reactions in which π‐coordination is transient. In this minireview, we describe the key reaction chemistry of arenes coordinated to a range of transition metals, including stereoselective reactions and industrially relevant syntheses. We also summarize outstanding examples of catalytic processes. Finally, we give perspectives on the future direction of the field, with respect to both reactions that are stoichiometric in activating metals and those employing catalytic metal",

author = "Luke Williams and Yunas Bhonoah and Wilkinson, {Luke Alexander} and James Walton",

note = " 2020 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH",

year = "2021",

month = jan,

day = "7",

doi = "10.1002/chem.202004621",

language = "English",

pages = "1--12",

journal = "Chemistry : A European Journal",

issn = "0947-6539",

publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - As nice as π: aromatic reactions activated by π‐coordination to transition metals

AU - Williams, Luke

AU - Bhonoah, Yunas

AU - Wilkinson, Luke Alexander

AU - Walton, James

N1 -  2020 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH

PY - 2021/1/7

Y1 - 2021/1/7

N2 - π‐Coordination of aromatic molecules to metals dramatically alters their reactivity. For example, coordinated carbons become more electrophilic and C‐H bonds of coordinated rings become more acidic. For many years, this change in reactivity has been used to trigger reactions that would not take place for uncoordinated arenes, however, there has been a recent resurgence in use of this technique, in part due to the development of catalytic reactions in which π‐coordination is transient. In this minireview, we describe the key reaction chemistry of arenes coordinated to a range of transition metals, including stereoselective reactions and industrially relevant syntheses. We also summarize outstanding examples of catalytic processes. Finally, we give perspectives on the future direction of the field, with respect to both reactions that are stoichiometric in activating metals and those employing catalytic metal

AB - π‐Coordination of aromatic molecules to metals dramatically alters their reactivity. For example, coordinated carbons become more electrophilic and C‐H bonds of coordinated rings become more acidic. For many years, this change in reactivity has been used to trigger reactions that would not take place for uncoordinated arenes, however, there has been a recent resurgence in use of this technique, in part due to the development of catalytic reactions in which π‐coordination is transient. In this minireview, we describe the key reaction chemistry of arenes coordinated to a range of transition metals, including stereoselective reactions and industrially relevant syntheses. We also summarize outstanding examples of catalytic processes. Finally, we give perspectives on the future direction of the field, with respect to both reactions that are stoichiometric in activating metals and those employing catalytic metal

U2 - 10.1002/chem.202004621

DO - 10.1002/chem.202004621

M3 - Article

SN - 0947-6539

SP - 1

EP - 12

JO - Chemistry : A European Journal

JF - Chemistry : A European Journal

ER -