Assessing variability of aerosols generated from e-Cigarettes

Darpan Das; Sarah Marie Alam El Din; Jairus Pulczinski; Jana N. Mihalic; Rui Chen; Joseph Bressler; Ana M. Rule; Gurumurthy Ramachandran

doi:10.1080/08958378.2022.2044414

Assessing variability of aerosols generated from e-Cigarettes

Darpan Das^*, Sarah Marie Alam El Din, Jairus Pulczinski, Jana N. Mihalic, Rui Chen, Joseph Bressler, Ana M. Rule, Gurumurthy Ramachandran

^*Corresponding author for this work

Environment and Geography

Research output: Contribution to journal › Article › peer-review

Abstract

While some in vitro and in vivo experiments have studied the toxic effects of e-cigarette (e-cig) components, the typical aerosol properties released from e-cigarettes have not been well characterized. In the present study, we characterized the variability in mass concentration and particle size distribution associated with the aerosol generation of different devices and e-liquid compositions in an experimental setup. The findings of this study indicate a large inter-day variability in the experiments, likely due to poor quality control in some e-cig devices, pointing to the need for a better understanding of all the factors affecting exposures in in vitro and in vivo experiments, and the development of standardized protocols for generation and measurement of e-cig aerosols.

Original language	English
Pages (from-to)	90-98
Number of pages	9
Journal	Inhalation Toxicology
Volume	34
Issue number	3-4
DOIs	https://doi.org/10.1080/08958378.2022.2044414
Publication status	Published - 11 Mar 2022

Bibliographical note

Publisher Copyright:
© 2022 Informa UK Limited, trading as Taylor & Francis Group.

Keywords

aerosols
in vivo
Vaping; variability

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10.1080/08958378.2022.2044414

Cite this

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title = "Assessing variability of aerosols generated from e-Cigarettes",

abstract = "While some in vitro and in vivo experiments have studied the toxic effects of e-cigarette (e-cig) components, the typical aerosol properties released from e-cigarettes have not been well characterized. In the present study, we characterized the variability in mass concentration and particle size distribution associated with the aerosol generation of different devices and e-liquid compositions in an experimental setup. The findings of this study indicate a large inter-day variability in the experiments, likely due to poor quality control in some e-cig devices, pointing to the need for a better understanding of all the factors affecting exposures in in vitro and in vivo experiments, and the development of standardized protocols for generation and measurement of e-cig aerosols.",

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AU - Das, Darpan

AU - Alam El Din, Sarah Marie

AU - Pulczinski, Jairus

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AU - Chen, Rui

AU - Bressler, Joseph

AU - Rule, Ana M.

AU - Ramachandran, Gurumurthy

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AB - While some in vitro and in vivo experiments have studied the toxic effects of e-cigarette (e-cig) components, the typical aerosol properties released from e-cigarettes have not been well characterized. In the present study, we characterized the variability in mass concentration and particle size distribution associated with the aerosol generation of different devices and e-liquid compositions in an experimental setup. The findings of this study indicate a large inter-day variability in the experiments, likely due to poor quality control in some e-cig devices, pointing to the need for a better understanding of all the factors affecting exposures in in vitro and in vivo experiments, and the development of standardized protocols for generation and measurement of e-cig aerosols.

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Assessing variability of aerosols generated from e-Cigarettes

Abstract

Bibliographical note

Keywords

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