Structurally intact tropical forests sequestered ~50% of global terrestrial carbon uptake over the 1990s and early 2000s, removing ~15% of anthropogenic CO2 emissions. Climate-driven vegetation models typically predict that this tropical forest ‘carbon sink’ will continue for decades. Here, we assess trends in the carbon sink using 244 structurally intact African tropical forests spanning 11 countries, we compare them with 321 published plots from Amazonia and investigate the underlying drivers of the trends. The carbon sink in live aboveground biomass in intact African tropical forests has been stable for the three decades to 2015, at 0.66 Mg C ha-1 yr-1 (95% CI:0.53-0.79), in contrast to the long-term decline in Amazonian forests. Thus, the carbon sink responses of Earth’s two largest expanses of tropical forest have diverged. The difference is largely driven by carbon losses from tree mortality, with no detectable multi-decadal trend in Africa and a long-term increase in Amazonia. Both continents show increasing tree growth, consistent with the expected net effect of rising atmospheric CO2 and air temperature. Despite the past stability of the African carbon sink, our data suggest a post-2010 increase in carbon losses, delayed compared to Amazonia, indicating asynchronous carbon sink saturation on the two continents. A statistical model including CO2, temperature, drought and forest dynamics accounts for the observed trends and indicates a long-term future decline in the African sink, while the Amazonian sink continues to rapidly weaken. Overall, the uptake of carbon into Earth’s intact tropical forests peaked in the 1990s. Given that the global terrestrial carbon sink is increasing in size, observations indicating greater recent carbon uptake into the Northern hemisphere landmass reinforce our conclusion that the intact tropical forest carbon sink has already saturated. This tropical forest sink saturation and ongoing decline has consequences for policies to stabilise Earth’s climate.