Beyond co-expression: pathway discovery for plant pharmaceuticals

Research output: Contribution to journalReview articlepeer-review

Abstract

Plant natural products have been an important source of medicinal molecules since ancient times. To gain access to the whole diversity of these molecules for pharmaceutical applications, it is important to understand their biosynthetic origins. Whilst co-expression is a reliable tool for identifying gene candidates, a variety of complementary methods can aid in screening or refining candidate selection. Here, we review recently employed plant biosynthetic pathway discovery approaches, and highlight future directions in the field.

Original languageEnglish
Article number103147
Number of pages8
JournalCURRENT OPINION IN BIOTECHNOLOGY
Volume88
DOIs
Publication statusAccepted/In press - 3 Jun 2024

Bibliographical note

© 2024 The Author(s). Published by Elsevier Ltd.

Funding Information:
We acknowledge funding from UKRI (MR/S01862X/1 and MR/X010260/1).

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