Breakthrough in the α-perchlorination of acyl chlorides

Franco Bellesia; Francesca Danna; Fulvia Felluga; Vincenzo Frenna; Franco Ghelfi; Andrew F. Parsons; Federico Reverberi; Domenico Spinelli

doi:10.1055/s-0031-1289678

Breakthrough in the α-perchlorination of acyl chlorides

Franco Bellesia, Francesca Danna, Fulvia Felluga, Vincenzo Frenna, Franco Ghelfi, Andrew F. Parsons, Federico Reverberi^*, Domenico Spinelli

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The preparation of -perchloroacyl chlorides, from reaction of the corresponding unfunctionalized acyl halides with chlorine, was efficiently achieved under base-catalysis, using a tetraalkylammonium chloride as catalyst. The process is solvent-free and the procedure is easy, inexpensive, and suitable for scale-up.

Original language	English
Pages (from-to)	605-609
Number of pages	5
Journal	Synthesis
Volume	44
Issue number	4
DOIs	https://doi.org/10.1055/s-0031-1289678
Publication status	Published - 2012

Keywords

2,2-dichloroacyl chlorides
acyl chlorides
base catalysis
chlorine
halogenation

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abstract = "The preparation of -perchloroacyl chlorides, from reaction of the corresponding unfunctionalized acyl halides with chlorine, was efficiently achieved under base-catalysis, using a tetraalkylammonium chloride as catalyst. The process is solvent-free and the procedure is easy, inexpensive, and suitable for scale-up.",

keywords = "2,2-dichloroacyl chlorides, acyl chlorides, base catalysis, chlorine, halogenation",

author = "Franco Bellesia and Francesca Danna and Fulvia Felluga and Vincenzo Frenna and Franco Ghelfi and Parsons, {Andrew F.} and Federico Reverberi and Domenico Spinelli",

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T1 - Breakthrough in the α-perchlorination of acyl chlorides

AU - Bellesia, Franco

AU - Danna, Francesca

AU - Felluga, Fulvia

AU - Frenna, Vincenzo

AU - Ghelfi, Franco

AU - Parsons, Andrew F.

AU - Reverberi, Federico

AU - Spinelli, Domenico

PY - 2012

Y1 - 2012

N2 - The preparation of -perchloroacyl chlorides, from reaction of the corresponding unfunctionalized acyl halides with chlorine, was efficiently achieved under base-catalysis, using a tetraalkylammonium chloride as catalyst. The process is solvent-free and the procedure is easy, inexpensive, and suitable for scale-up.

AB - The preparation of -perchloroacyl chlorides, from reaction of the corresponding unfunctionalized acyl halides with chlorine, was efficiently achieved under base-catalysis, using a tetraalkylammonium chloride as catalyst. The process is solvent-free and the procedure is easy, inexpensive, and suitable for scale-up.

KW - 2,2-dichloroacyl chlorides

KW - acyl chlorides

KW - base catalysis

KW - chlorine

KW - halogenation

UR - http://www.scopus.com/inward/record.url?scp=84857030538&partnerID=8YFLogxK

U2 - 10.1055/s-0031-1289678

DO - 10.1055/s-0031-1289678

M3 - Article

AN - SCOPUS:84857030538

SN - 0039-7881

VL - 44

SP - 605

EP - 609

JO - Synthesis

JF - Synthesis

IS - 4

ER -

Breakthrough in the α-perchlorination of acyl chlorides

Abstract

Keywords

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