Burden and management of non-cancerous HPV-related conditions: HPV-6/11 disease

Charles J. N. Lacey, Catherine M. Lowndes, Keerti V. Shah

Research output: Contribution to journalArticlepeer-review

Abstract

Human Papillomavirus (HPV)-6 and -11 are the causative agents of ano-genital warts (GWs) and recurrent respiratory papillomatosis (RRP). They are low-risk HPV types that are uncommonly found in malignant lesions. GWs are an extremely prevalent sexually transmitted disease, whereas RRP is a rare disease that can be life threatening and requires multiple surgical procedures. GWs and RRP cause substantial healthcare costs. A quadrivalent HPV-6/11/16/18 vaccine (Merck/SPMSD) has shown essentially 100% protection against GWs in women in early studies. Cost-effectiveness analyses are needed to assess the benefits of the HPV-6/11 virus-like particle (VLP) components of the quadrivalent vaccine in population-based vaccination programmes. (c) 2006 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)35-41
Number of pages7
JournalVaccine
Volume24
DOIs
Publication statusPublished - 31 Aug 2006

Keywords

  • HPV-6/11
  • management
  • non-cancerous
  • RECURRENT RESPIRATORY PAPILLOMATOSIS
  • PAPILLOMAVIRUS-RELATED DISEASE
  • RANDOMIZED CONTROLLED-TRIAL
  • EXTERNAL ANOGENITAL WARTS
  • GENITAL WARTS
  • RISK-FACTORS
  • ECONOMIC BURDEN
  • INFECTION
  • POPULATION
  • TYPE-11

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