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Can simvastatin improve erectile function and health-related quality of life in men aged >40 years with erectile dysfunction? Rationale and design of the Erectile Dysfunction and Statins (EDS) Trial [ISRCTN66772971](1)

Research output: Contribution to journalArticle


  • Daksha Trivedi
  • Michael Kirby
  • Felicity Norman
  • Izabela Przybytniak
  • Shehzad Ali
  • David M Wellsted


Publication details

JournalBJU International
DatePublished - Dec 2011
Issue number11
Number of pages5
Pages (from-to)1850-4
Original languageEnglish


What's known on the subject? and What will the study add? Erectile dysfunction is often associated with endothelial dysfunction. It is also recognized as a marker for underlying vascular disease. This study tests the hypothesis that statin therapy may improve erectile function and also reduce the risk of future cardiovascular events via a reduction in serum cholesterol and by improving endothelial function. The study will also determine whether the treatment improves quality of life related to sexual function.

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