The York Research Database

Overexpression of Placental Growth Factor in Stromal Cells from Benign Prostatic Hyperplasia: Another Piece in the Puzzle?

Devlin, C., Frame, F. M., Archer, L., Mann, V. M., Walker, H., Simms, M. S., Berney, D. M., Collins, A. & Maitland, N. J., 14 Sep 2020

Article in European Urology Open Science

STAT3 inhibition with Galiellalactone effectively targets the prostate cancer stem-like cell population."

Canesin, G., Maggio, V., Palominos, M., Stiehm, A., Contreras, H. R., Castellón, E. A., Morote, J., Paciucci, R., Maitland, N. J., Bjartell, A. & Hellsten, R., 18 Aug 2020

Article in Scientific Reports

Assessing the Advantages, Limitations and Potential of Human Primary Prostate Epithelial Cells as a Pre-clinical Model for Prostate Cancer Research

Frame, F. M., Noble, A. R., O'Toole, P., Marrison, J., Godden, T., O'Brien, A. & Maitland, N. J., 2 Oct 2019

Article in Advances in experimental medicine and biology

Resolution of Cellular Heterogeneity in Human Prostate Cancers: Implications for Diagnosis and Treatment

Maitland, N. J., Frame, F. M., Rane, J. K., Erb, H. H., Packer, J. R., Archer, L. K. & Pellacani, D., 2 Oct 2019

Review article in Advances in experimental medicine and biology

Notch signalling is a potential resistance mechanism of progenitor cells within patient-derived prostate cultures following ROS-inducing treatments

Packer, J. R., Hirst, A. M., Droop, A. P., Adamson, R., Simms, M. S., Mann, V. M., Frame, F. M., O'Connell, D. & Maitland, N. J., 17 Sep 2019

Article in FEBS Letters

S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth

Casara, P., Davidson, J., Claperon, A., Toumelin-Braizat, G. L., Vogler, M., Bruno, A., Chanrion, M., Lysiak-Auvity, G., Diguarher, T. L., Starck, J-B., Chen, I., Whitehead, N., Graham, C., Matassova, N., Dokurno, P., Pedder, C., Wang, Y., Qiu, S., Girard, A-M., Schneider, E. & 18 others, Gravé, F., Studeny, A., Guasconi, G., Rocchetti, F., Maïga, S., Henlin, J-M., Colland, F., Kraus-Berthier, L., Gouill, S. L., Dyer, M. JS., Hubbard, R., Wood, M., Amiot, M., Cohen, G. M., Hickman, J. A., Morris, E., Murray, J. & Geneste, O., 13 Apr 2018

Article in Oncotarget

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer

Butler, D. E., Marlein, C., Walker, H. F., Frame, F. M., Mann, V. M., Simms, M. S., Davies, B. R., Collins, A. T. & Maitland, N. J., 23 May 2017

Article in Oncotarget

IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines

Thurber, A., Nelson, M., Frost, C., Levin, M., Brackenbury, W. J. & Kaplan, D. L., 21 Mar 2017

Article in Oncotarget

Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia

Laidlaw, K. M. E., Berhan, S., Liu, S., Silvestri, G., Holyoake, T. L., Frank, D. A., Aggarwal, B., Bonner, M. Y., Perrotti, D., Jørgensen, H. G. & Arbiser, J. L., 9 Aug 2016

Article in Oncotarget

Inhibition of the glucocorticoid receptor results in an enhanced miR-99a/100-mediated radiation response in stem-like cells from human prostate cancers

Rane, J. K., Erb, H. H., Nappo, G., Mann, V. M., Simms, M. S., Collins, A. T., Visakorpi, T. & Maitland, N. J., 21 Jun 2016

Article in Oncotarget