Cascade reactions of 1,2,4-triazines: direct thermochemical access to functionalized 4,5-dihydroazocines

S A  Raw; R J K  Taylor

doi:10.1016/j.tetlet.2004.09.169

Cascade reactions of 1,2,4-triazines: direct thermochemical access to functionalized 4,5-dihydroazocines

S A Raw, R J K Taylor

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A rapid, facile approach to functionalized 4,5-dihydroazociries has been developed, exploiting a one-pot reaction cascade from easily-prepared 3-(ethoxycarbonyl)-5-phenyl-1,2,4-triazine, cyclobutanone and secondary amines. (C) 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	8607-8610
Number of pages	4
Journal	Tetrahedron Letters
Volume	45
Issue number	47
DOIs	https://doi.org/10.1016/j.tetlet.2004.09.169
Publication status	Published - 15 Nov 2004

Keywords

dihydroazocine
1,2,4-triazine
cascade
pericyclic
thermochemical
ENANTIOSELECTIVE ENONE EPOXIDATIONS
ENANTIOPURE GUANIDINE BASES
TANDEM OXIDATION PROCESSES
DIELS-ALDER REACTION
HETEROCYCLIC AZADIENES
SUBSTITUTED PYRIDINES
AGENTS
PHOTOCYCLOADDITION
METHODOLOGY
INHIBITORS

Access to Document

10.1016/j.tetlet.2004.09.169

Cite this

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title = "Cascade reactions of 1,2,4-triazines: direct thermochemical access to functionalized 4,5-dihydroazocines",

abstract = "A rapid, facile approach to functionalized 4,5-dihydroazociries has been developed, exploiting a one-pot reaction cascade from easily-prepared 3-(ethoxycarbonyl)-5-phenyl-1,2,4-triazine, cyclobutanone and secondary amines. (C) 2004 Elsevier Ltd. All rights reserved.",

keywords = "dihydroazocine, 1,2,4-triazine, cascade, pericyclic, thermochemical, ENANTIOSELECTIVE ENONE EPOXIDATIONS, ENANTIOPURE GUANIDINE BASES, TANDEM OXIDATION PROCESSES, DIELS-ALDER REACTION, HETEROCYCLIC AZADIENES, SUBSTITUTED PYRIDINES, AGENTS, PHOTOCYCLOADDITION, METHODOLOGY, INHIBITORS",

author = "Raw, {S A} and Taylor, {R J K}",

year = "2004",

month = nov,

day = "15",

doi = "10.1016/j.tetlet.2004.09.169",

language = "English",

volume = "45",

pages = "8607--8610",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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number = "47",

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TY - JOUR

T1 - Cascade reactions of 1,2,4-triazines: direct thermochemical access to functionalized 4,5-dihydroazocines

AU - Raw, S A

AU - Taylor, R J K

PY - 2004/11/15

Y1 - 2004/11/15

N2 - A rapid, facile approach to functionalized 4,5-dihydroazociries has been developed, exploiting a one-pot reaction cascade from easily-prepared 3-(ethoxycarbonyl)-5-phenyl-1,2,4-triazine, cyclobutanone and secondary amines. (C) 2004 Elsevier Ltd. All rights reserved.

AB - A rapid, facile approach to functionalized 4,5-dihydroazociries has been developed, exploiting a one-pot reaction cascade from easily-prepared 3-(ethoxycarbonyl)-5-phenyl-1,2,4-triazine, cyclobutanone and secondary amines. (C) 2004 Elsevier Ltd. All rights reserved.

KW - dihydroazocine

KW - 1,2,4-triazine

KW - cascade

KW - pericyclic

KW - thermochemical

KW - ENANTIOSELECTIVE ENONE EPOXIDATIONS

KW - ENANTIOPURE GUANIDINE BASES

KW - TANDEM OXIDATION PROCESSES

KW - DIELS-ALDER REACTION

KW - HETEROCYCLIC AZADIENES

KW - SUBSTITUTED PYRIDINES

KW - AGENTS

KW - PHOTOCYCLOADDITION

KW - METHODOLOGY

KW - INHIBITORS

U2 - 10.1016/j.tetlet.2004.09.169

DO - 10.1016/j.tetlet.2004.09.169

M3 - Article

SN - 0040-4039

VL - 45

SP - 8607

EP - 8610

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 47

ER -