By the same authors

From the same journal

Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

Research output: Contribution to journalArticlepeer-review

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Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG) : Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. / Waszkowycz, Bohdan; Smith, Kate M.; McGonagle, Alison E.; Jordan, Allan M.; Acton, Ben ; Fairweather, Emma E.; Griffiths, Louise A. ; Hamilton, Niall M.; Hamilton, Nicola S. ; Hitchin, James R. ; Hutton, Colin P.; James, Dominic I.; Jones, Clifford D.; Jones, Stuart; Mould, Daniel P.; Small, Helen F.; Stowell, Alexandra I. J. ; Tucker, Julie Ann; Waddell, Ian D.; Ogilvie, Donald J.

In: JOURNAL OF MEDICINAL CHEMISTRY, Vol. 61, No. 23, 13.12.2018, p. 10767-10792.

Research output: Contribution to journalArticlepeer-review

Harvard

Waszkowycz, B, Smith, KM, McGonagle, AE, Jordan, AM, Acton, B, Fairweather, EE, Griffiths, LA, Hamilton, NM, Hamilton, NS, Hitchin, JR, Hutton, CP, James, DI, Jones, CD, Jones, S, Mould, DP, Small, HF, Stowell, AIJ, Tucker, JA, Waddell, ID & Ogilvie, DJ 2018, 'Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides', JOURNAL OF MEDICINAL CHEMISTRY, vol. 61, no. 23, pp. 10767-10792. https://doi.org/10.1021/acs.jmedchem.8b01407

APA

Waszkowycz, B., Smith, K. M., McGonagle, A. E., Jordan, A. M., Acton, B., Fairweather, E. E., Griffiths, L. A., Hamilton, N. M., Hamilton, N. S., Hitchin, J. R., Hutton, C. P., James, D. I., Jones, C. D., Jones, S., Mould, D. P., Small, H. F., Stowell, A. I. J., Tucker, J. A., Waddell, I. D., & Ogilvie, D. J. (2018). Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. JOURNAL OF MEDICINAL CHEMISTRY, 61(23), 10767-10792. https://doi.org/10.1021/acs.jmedchem.8b01407

Vancouver

Waszkowycz B, Smith KM, McGonagle AE, Jordan AM, Acton B, Fairweather EE et al. Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. JOURNAL OF MEDICINAL CHEMISTRY. 2018 Dec 13;61(23):10767-10792. https://doi.org/10.1021/acs.jmedchem.8b01407

Author

Waszkowycz, Bohdan ; Smith, Kate M. ; McGonagle, Alison E. ; Jordan, Allan M. ; Acton, Ben ; Fairweather, Emma E. ; Griffiths, Louise A. ; Hamilton, Niall M. ; Hamilton, Nicola S. ; Hitchin, James R. ; Hutton, Colin P. ; James, Dominic I. ; Jones, Clifford D. ; Jones, Stuart ; Mould, Daniel P. ; Small, Helen F. ; Stowell, Alexandra I. J. ; Tucker, Julie Ann ; Waddell, Ian D. ; Ogilvie, Donald J. / Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG) : Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. In: JOURNAL OF MEDICINAL CHEMISTRY. 2018 ; Vol. 61, No. 23. pp. 10767-10792.

Bibtex - Download

@article{d77326594d1e4c5786cb813f71808021,
title = "Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides",
author = "Bohdan Waszkowycz and Smith, {Kate M.} and McGonagle, {Alison E.} and Jordan, {Allan M.} and Ben Acton and Fairweather, {Emma E.} and Griffiths, {Louise A.} and Hamilton, {Niall M.} and Hamilton, {Nicola S.} and Hitchin, {James R.} and Hutton, {Colin P.} and James, {Dominic I.} and Jones, {Clifford D.} and Stuart Jones and Mould, {Daniel P.} and Small, {Helen F.} and Stowell, {Alexandra I. J.} and Tucker, {Julie Ann} and Waddell, {Ian D.} and Ogilvie, {Donald J.}",
note = "{\textcopyright} 2018 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details.",
year = "2018",
month = dec,
day = "13",
doi = "10.1021/acs.jmedchem.8b01407",
language = "English",
volume = "61",
pages = "10767--10792",
journal = "JOURNAL OF MEDICINAL CHEMISTRY",
issn = "0022-2623",
publisher = "American Chemical Society",
number = "23",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG)

T2 - Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

AU - Waszkowycz, Bohdan

AU - Smith, Kate M.

AU - McGonagle, Alison E.

AU - Jordan, Allan M.

AU - Acton, Ben

AU - Fairweather, Emma E.

AU - Griffiths, Louise A.

AU - Hamilton, Niall M.

AU - Hamilton, Nicola S.

AU - Hitchin, James R.

AU - Hutton, Colin P.

AU - James, Dominic I.

AU - Jones, Clifford D.

AU - Jones, Stuart

AU - Mould, Daniel P.

AU - Small, Helen F.

AU - Stowell, Alexandra I. J.

AU - Tucker, Julie Ann

AU - Waddell, Ian D.

AU - Ogilvie, Donald J.

N1 - © 2018 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

PY - 2018/12/13

Y1 - 2018/12/13

U2 - 10.1021/acs.jmedchem.8b01407

DO - 10.1021/acs.jmedchem.8b01407

M3 - Article

VL - 61

SP - 10767

EP - 10792

JO - JOURNAL OF MEDICINAL CHEMISTRY

JF - JOURNAL OF MEDICINAL CHEMISTRY

SN - 0022-2623

IS - 23

ER -