Chiral recognition at self-assembled multivalent (SAMul) nanoscale interfaces – enantioselectivity in polyanion binding

Ching Wan Chan, Eric Laurini, Paola Posocco, Sabrina Pricl, David Kelham Smith

Research output: Contribution to journalArticlepeer-review


Self-assembled multivalent (SAMul) ligands based on palmitic acid functionalised with cationic L/D-lysine bind polyanionic heparin or DNA with no chiral preference. Inserting a glycine spacer unit switches on chiral discrimination – a rare example of controlled chiral recognition at a SAMul nanoscale interface.
Original languageEnglish
Pages (from-to)10540-10543
Number of pages4
JournalChemical Communications
Early online date5 Aug 2016
Publication statusE-pub ahead of print - 5 Aug 2016

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