Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease:  5-year follow-up of multicentre randomised trial (the REFLUX trial)

Adrian Grant; C. Boachie; S. Cotton; Rita Faria; Laura Bojke; David Epstein; Craig Ramsay; Maria Belen Corbacho Martin; Mark Sculpher; Z.H. Krukowski; R. Heading; M. Campbell

doi:10.3310/hta17220

Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial)

Adrian Grant, C. Boachie, S. Cotton, Rita Faria, Laura Bojke, David Epstein, Craig Ramsay, Maria Belen Corbacho Martin, Mark Sculpher, Z.H. Krukowski, R. Heading, M. Campbell

Research output: Contribution to journal › Article › peer-review

Abstract

Study found that, after 5 years, laparoscopic fundoplication gives sustained better relief of gastro-oesophageal reflux disease symptoms than continued medical management, with associated improved health-related quality of life, and that, despite being initially more costly, a surgical policy is highly likely to be cost-effective.

Original language	English
Pages (from-to)	1-167
Number of pages	167
Journal	Health technology assessment
Volume	17
Issue number	22
DOIs	https://doi.org/10.3310/hta17220
Publication status	Published - Jun 2013

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10.3310/hta17220

http://www.journalslibrary.nihr.ac.uk/hta/volume-17/issue-22

Cite this

Grant, A., Boachie, C., Cotton, S., Faria, R., Bojke, L., Epstein, D., Ramsay, C., Corbacho Martin, M. B., Sculpher, M., Krukowski, Z. H., Heading, R., & Campbell, M. (2013). Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial). Health technology assessment, 17(22), 1-167. https://doi.org/10.3310/hta17220

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abstract = "Study found that, after 5 years, laparoscopic fundoplication gives sustained better relief of gastro-oesophageal reflux disease symptoms than continued medical management, with associated improved health-related quality of life, and that, despite being initially more costly, a surgical policy is highly likely to be cost-effective. ",

author = "Adrian Grant and C. Boachie and S. Cotton and Rita Faria and Laura Bojke and David Epstein and Craig Ramsay and {Corbacho Martin}, {Maria Belen} and Mark Sculpher and Z.H. Krukowski and R. Heading and M. Campbell",

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Grant, A, Boachie, C, Cotton, S, Faria, R , Bojke, L, Epstein, D, Ramsay, C, Corbacho Martin, MB , Sculpher, M, Krukowski, ZH, Heading, R & Campbell, M 2013, 'Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial)', Health technology assessment, vol. 17, no. 22, pp. 1-167. https://doi.org/10.3310/hta17220

Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial). / Grant, Adrian; Boachie, C.; Cotton, S. et al.
In: Health technology assessment, Vol. 17, No. 22, 06.2013, p. 1-167.

Research output: Contribution to journal › Article › peer-review

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AB - Study found that, after 5 years, laparoscopic fundoplication gives sustained better relief of gastro-oesophageal reflux disease symptoms than continued medical management, with associated improved health-related quality of life, and that, despite being initially more costly, a surgical policy is highly likely to be cost-effective.

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