Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial)

Adrian Grant, C. Boachie, S. Cotton, Rita Faria, Laura Bojke, David Epstein, Craig Ramsay, Maria Belen Corbacho Martin, Mark Sculpher, Z.H. Krukowski, R. Heading, M. Campbell

Research output: Contribution to journalArticlepeer-review


Study found that, after 5 years, laparoscopic fundoplication gives sustained better relief of gastro-oesophageal reflux disease symptoms than continued medical management, with associated improved health-related quality of life, and that, despite being initially more costly, a surgical policy is highly likely to be cost-effective.
Original languageEnglish
Pages (from-to)1-167
Number of pages167
JournalHealth technology assessment
Issue number22
Publication statusPublished - Jun 2013

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