By the same authors

From the same journal

CNGCs: prime targets of plant cyclic nucleotide signalling?

Research output: Contribution to journalLiterature review

Author(s)

Department/unit(s)

Publication details

JournalTRENDS IN PLANT SCIENCE
DatePublished - Jun 2003
Issue number6
Volume8
Number of pages8
Pages (from-to)286-293
Original languageEnglish

Abstract

Cyclic nucleotide-gated channels (CNGCs) are a recently identified family of plant ion channels. They show a high degree of similarity to Shaker-type voltage-gated channels and contain a C-terminal cyclic nucleotide-binding domain with an overlapping calmodulin-binding domain. Heterologously expressed plant CNGCs; show activation by cyclic nucleotides and permeability to monovalent and divalent cations. In plants, downstream effectors of cyclic nucleotide signals have so far remained obscure, and CNGCs might be their prime targets. The unique position of CNGCs as ligand-gated Ca2+-permeable channels suggests that they function at key sites where cyclic nucleotide and Ca2+ signalling pathways interact. Such processes include plant defence responses, and two recently characterized Arabidopsis mutants in CNGC genes indeed show altered pathogen responses.

    Research areas

  • GATED CATION CHANNEL, CALMODULIN-BINDING TRANSPORTER, PROGRAMMED CELL-DEATH, CULTURED CARROT CELLS, PLASMA-MEMBRANE, ARABIDOPSIS-THALIANA, ION CHANNELS, HYPERSENSITIVE RESPONSE, VICIA-FABA, CALCIUM-CALMODULIN

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations