Cold atmospheric pressure plasma jet interactions with plasmid DNA

D. O'Connell, L. J. Cox, W. B. Hyland, S. J. McMahon, S. Reuter, W. G. Graham, T. Gans, F. J. Currell

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The effect of a cold (<40 degrees C) radio frequency-driven atmospheric pressure plasma jet on plasmid DNA has been investigated. Gel electrophoresis was used to analyze the DNA forms post-treatment. The experimental data are fitted to a rate equation model that allows for quantitative determination of the rates of single and double strand break formation. The formation of double strand breaks correlates well with the atomic oxygen density. Taken with other measurements, this indicates that neutral components in the jet are effective in inducing double strand breaks. (C) 2011 American Institute of Physics. [doi:10.1063/1.3521502]

Original languageEnglish
Article number043701
Pages (from-to)1-3
Number of pages3
JournalApplied Physics Letters
Issue number4
Publication statusPublished - 24 Jan 2011



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