Cold atmospheric pressure plasma jets: Interaction with plasmid DNA and tailored electron heating using dual-frequency excitation

K. Niemi*, C. O'Neill, L. J. Cox, J. Waskoenig, W. B. Hyland, S. J. McMahon, S. Reuter, F. J. Currell, W. G. Graham, D. O'Connell, T. Gans

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Recent progress in plasma science and technology has enabled the development of a new generation of stable cold non-equilibrium plasmas operating at ambient atmospheric pressure. This opens horizons for new plasma technologies, in particular in the emerging field of plasma medicine. These non-equilibrium plasmas are very efficient sources for energy transport through reactive neutral particles (radicals and metastables), charged particles (ions and electrons), UV radiation, and electro-magnetic fields. The effect of a cold radio frequency-driven atmospheric pressure plasma jet on plasmid DNA has been investigated. The formation of double strand breaks correlates well with the atomic oxygen density. Taken with other measurements, this indicates that neutral components in the jet are effective in inducing double strand breaks. Plasma manipulation techniques for controlled energy delivery are highly desirable. Numerical simulations are employed for detailed investigations of the electron dynamics, which determines the generation of reactive species. New concepts based on non-linear power dissipation promise superior strategies to control energy transport for tailored technological exploitations.

Original languageEnglish
Title of host publication17th International Conference on Atomic Processes in Plasmas (ICAPiP)
EditorsK Aggarwal, F Shearer
Place of PublicationMELVILLE
PublisherAmerican Institute of Physics
ISBN (Print)978-0-7354-1029-9
Publication statusPublished - 2012
Event17th International Conference on Atomic Processes in Plasmas (ICAPiP) - Belfast
Duration: 19 Jul 201122 Jul 2011

Publication series

NameAIP Conference Proceedings
ISSN (Print)0094-243X


Conference17th International Conference on Atomic Processes in Plasmas (ICAPiP)


  • plasma-medicine
  • atmospheric pressure plasmas
  • Cold plasmas
  • radio-frequency plasmas
  • dual-frequency plasmas

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