Combined biological and chemical catalysis in the preparation of oxycodone

Neil Charles Bruce; Adam J. Walker

doi:10.1016/j.tet.2003.11.063

Combined biological and chemical catalysis in the preparation of oxycodone

Neil Charles Bruce, Adam J. Walker

CNAP

Research output: Contribution to journal › Article › peer-review

Abstract

The opioid oxycodone was produced from codeine, using a combination of chemical and biological catalysis. The use of novel functionalized ionic liquids permitted this reaction to be performed in a single solvent.

Original language	English
Pages (from-to)	561-668
Number of pages	7
Journal	Tetrahedron
Volume	60
Issue number	3
DOIs	https://doi.org/10.1016/j.tet.2003.11.063
Publication status	Published - 12 Jan 2004

Keywords

BIOCATALYSIS
IONIC LIQUID
HYDRATION
OXYCODONE

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10.1016/j.tet.2003.11.063

http://www.sciencedirect.com/science/article/pii/S0040402003019197

Gr/S25203/01
Bruce, N. C. (Principal investigator)
EPSRC
1/10/03 → 31/01/07
Project: Research project (funded) › Research

Cite this

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title = "Combined biological and chemical catalysis in the preparation of oxycodone",

abstract = "The opioid oxycodone was produced from codeine, using a combination of chemical and biological catalysis. The use of novel functionalized ionic liquids permitted this reaction to be performed in a single solvent.",

keywords = "BIOCATALYSIS, IONIC LIQUID, HYDRATION, OXYCODONE",

author = "Bruce, {Neil Charles} and Walker, {Adam J.}",

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AU - Bruce, Neil Charles

AU - Walker, Adam J.

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Y1 - 2004/1/12

N2 - The opioid oxycodone was produced from codeine, using a combination of chemical and biological catalysis. The use of novel functionalized ionic liquids permitted this reaction to be performed in a single solvent.

AB - The opioid oxycodone was produced from codeine, using a combination of chemical and biological catalysis. The use of novel functionalized ionic liquids permitted this reaction to be performed in a single solvent.

KW - BIOCATALYSIS

KW - IONIC LIQUID

KW - HYDRATION

KW - OXYCODONE

U2 - 10.1016/j.tet.2003.11.063

DO - 10.1016/j.tet.2003.11.063

M3 - Article

SN - 0040-4020

VL - 60

SP - 561

EP - 668

JO - Tetrahedron

JF - Tetrahedron

IS - 3

ER -

Combined biological and chemical catalysis in the preparation of oxycodone

Abstract

Keywords

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Projects

Gr/S25203/01

Cite this