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Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial

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Computerised cognitive behaviour therapy for depression in adolescents : study protocol for a feasibility randomised controlled trial. / Wright, Barry John Debenham; Tindall, Lucy; Littlewood, Elizabeth; Adamson, Joy; Allgar, Victoria; Bennett, Sophie; Gilbody, Simon; Verduyn, Chrissie; Alderson-Day, Ben; Dyson, Lisa; Trépel, Dominic; Ali, Shehzad.

In: BMJ Open, Vol. 4, No. 10, e006488, 31.10.2014.

Research output: Contribution to journalArticle

Harvard

Wright, BJD, Tindall, L, Littlewood, E, Adamson, J, Allgar, V, Bennett, S, Gilbody, S, Verduyn, C, Alderson-Day, B, Dyson, L, Trépel, D & Ali, S 2014, 'Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial', BMJ Open, vol. 4, no. 10, e006488. https://doi.org/10.1136/bmjopen-2014-006488

APA

Wright, B. J. D., Tindall, L., Littlewood, E., Adamson, J., Allgar, V., Bennett, S., ... Ali, S. (2014). Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial. BMJ Open, 4(10), [e006488]. https://doi.org/10.1136/bmjopen-2014-006488

Vancouver

Wright BJD, Tindall L, Littlewood E, Adamson J, Allgar V, Bennett S et al. Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial. BMJ Open. 2014 Oct 31;4(10). e006488. https://doi.org/10.1136/bmjopen-2014-006488

Author

Wright, Barry John Debenham ; Tindall, Lucy ; Littlewood, Elizabeth ; Adamson, Joy ; Allgar, Victoria ; Bennett, Sophie ; Gilbody, Simon ; Verduyn, Chrissie ; Alderson-Day, Ben ; Dyson, Lisa ; Trépel, Dominic ; Ali, Shehzad. / Computerised cognitive behaviour therapy for depression in adolescents : study protocol for a feasibility randomised controlled trial. In: BMJ Open. 2014 ; Vol. 4, No. 10.

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@article{781b86f31c7148bb8c8d4fc119dd74a4,
title = "Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial",
abstract = "Introduction: The 1 year prevalence of depression in adolescents is about 2{\%}. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computeradministered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Methods and analysis: Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approached to participate. Consenting participants will be randomised to either a CCBT programme (Stressbusters) or accessing selected websites providing information about low mood/depression. The primary outcome measure will be the Beck Depression Inventory (BDI). Participants will also complete generic health measures (EQ5D-Y, HUI2) and resource use questionnaires to examine the feasibility of cost-effectiveness analysis. Questionnaires will be completed at baseline, 4 and 12-month follow-ups. Progress and risk will be monitored via the MFQ administered at each treatment session. The acceptability of a CCBT programme to adolescents; and the willingness of clinicians to recruit participants and of participants to be randomised, recruitment rates, attrition rates and questionnaire completion rates will be collected for feasibility analysis. We will estimate 'numbers needed' to plan a fully powered RCT of clinical and cost-effectiveness. Ethics and dissemination: The current trial protocol received a favourable ethical opinion from Leeds (West) Research and Ethics Committee. (Reference: 10/H1307/137). Trial registration number: ISRCTN31219579.",
author = "Wright, {Barry John Debenham} and Lucy Tindall and Elizabeth Littlewood and Joy Adamson and Victoria Allgar and Sophie Bennett and Simon Gilbody and Chrissie Verduyn and Ben Alderson-Day and Lisa Dyson and Dominic Tr{\'e}pel and Shehzad Ali",
note = "Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.",
year = "2014",
month = "10",
day = "31",
doi = "10.1136/bmjopen-2014-006488",
language = "English",
volume = "4",
journal = "BMJ Open",
issn = "2044-6055",
publisher = "British Medical Journal Publishing Group",
number = "10",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Computerised cognitive behaviour therapy for depression in adolescents

T2 - BMJ Open

AU - Wright, Barry John Debenham

AU - Tindall, Lucy

AU - Littlewood, Elizabeth

AU - Adamson, Joy

AU - Allgar, Victoria

AU - Bennett, Sophie

AU - Gilbody, Simon

AU - Verduyn, Chrissie

AU - Alderson-Day, Ben

AU - Dyson, Lisa

AU - Trépel, Dominic

AU - Ali, Shehzad

N1 - Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

PY - 2014/10/31

Y1 - 2014/10/31

N2 - Introduction: The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computeradministered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Methods and analysis: Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approached to participate. Consenting participants will be randomised to either a CCBT programme (Stressbusters) or accessing selected websites providing information about low mood/depression. The primary outcome measure will be the Beck Depression Inventory (BDI). Participants will also complete generic health measures (EQ5D-Y, HUI2) and resource use questionnaires to examine the feasibility of cost-effectiveness analysis. Questionnaires will be completed at baseline, 4 and 12-month follow-ups. Progress and risk will be monitored via the MFQ administered at each treatment session. The acceptability of a CCBT programme to adolescents; and the willingness of clinicians to recruit participants and of participants to be randomised, recruitment rates, attrition rates and questionnaire completion rates will be collected for feasibility analysis. We will estimate 'numbers needed' to plan a fully powered RCT of clinical and cost-effectiveness. Ethics and dissemination: The current trial protocol received a favourable ethical opinion from Leeds (West) Research and Ethics Committee. (Reference: 10/H1307/137). Trial registration number: ISRCTN31219579.

AB - Introduction: The 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computeradministered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). Methods and analysis: Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approached to participate. Consenting participants will be randomised to either a CCBT programme (Stressbusters) or accessing selected websites providing information about low mood/depression. The primary outcome measure will be the Beck Depression Inventory (BDI). Participants will also complete generic health measures (EQ5D-Y, HUI2) and resource use questionnaires to examine the feasibility of cost-effectiveness analysis. Questionnaires will be completed at baseline, 4 and 12-month follow-ups. Progress and risk will be monitored via the MFQ administered at each treatment session. The acceptability of a CCBT programme to adolescents; and the willingness of clinicians to recruit participants and of participants to be randomised, recruitment rates, attrition rates and questionnaire completion rates will be collected for feasibility analysis. We will estimate 'numbers needed' to plan a fully powered RCT of clinical and cost-effectiveness. Ethics and dissemination: The current trial protocol received a favourable ethical opinion from Leeds (West) Research and Ethics Committee. (Reference: 10/H1307/137). Trial registration number: ISRCTN31219579.

UR - http://www.scopus.com/inward/record.url?scp=84911377606&partnerID=8YFLogxK

U2 - 10.1136/bmjopen-2014-006488

DO - 10.1136/bmjopen-2014-006488

M3 - Article

VL - 4

JO - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 10

M1 - e006488

ER -