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Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial

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Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial. / Horn, Eva K; van Benthem, Tjeerd B; Hakkaart-van Roijen, Leona; van Marwijk, Harm W J; Beekman, Aartjan T F; Rutten, Frans F; van der Feltz-Cornelis, Christina M.

In: BMC Health Services Research, Vol. 7, 26.02.2007, p. 28.

Research output: Contribution to journalArticle

Harvard

Horn, EK, van Benthem, TB, Hakkaart-van Roijen, L, van Marwijk, HWJ, Beekman, ATF, Rutten, FF & van der Feltz-Cornelis, CM 2007, 'Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial', BMC Health Services Research, vol. 7, pp. 28. https://doi.org/10.1186/1472-6963-7-28

APA

Horn, E. K., van Benthem, T. B., Hakkaart-van Roijen, L., van Marwijk, H. W. J., Beekman, A. T. F., Rutten, F. F., & van der Feltz-Cornelis, C. M. (2007). Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial. BMC Health Services Research, 7, 28. https://doi.org/10.1186/1472-6963-7-28

Vancouver

Horn EK, van Benthem TB, Hakkaart-van Roijen L, van Marwijk HWJ, Beekman ATF, Rutten FF et al. Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial. BMC Health Services Research. 2007 Feb 26;7:28. https://doi.org/10.1186/1472-6963-7-28

Author

Horn, Eva K ; van Benthem, Tjeerd B ; Hakkaart-van Roijen, Leona ; van Marwijk, Harm W J ; Beekman, Aartjan T F ; Rutten, Frans F ; van der Feltz-Cornelis, Christina M. / Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial. In: BMC Health Services Research. 2007 ; Vol. 7. pp. 28.

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@article{59c13fd6810740dfb07823c8b60f684f,
title = "Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial",
abstract = "BACKGROUND: Depressive disorder is one of the most common disorders, and is highly prevalent in chronically ill patients. The presence of comorbid depression has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Early diagnosis and well-organized treatment of depression has a positive influence on these aspects. Earlier research in the USA has reported good results with regard to the treatment of depression with a collaborative care approach and an antidepressant algorithm. In the UK 'Problem Solving Treatment' has proved to be feasible. However, in the general hospital setting this approach has not yet been evaluated.METHODS/DESIGN: CC: DIM (Collaborative Care: Depression Initiative in the Medical setting) is a two-armed randomised controlled trial with randomisation at patient level. The aim of the trial is to evaluate the treatment of depressive disorder in general hospitals in the Netherlands based on a collaborative care framework, including contracting, 'Problem Solving Treatment', antidepressant algorithm, and manual-guided self-help. 126 outpatients with diabetes mellitus, chronic obstructive pulmonary disease, or cardiovascular diseases will be randomised to either the intervention group or the control group. Patients will be included if they have been diagnosed with moderate to severe depression, based on the DSM-IV criteria in a two-step screening method. The intervention group will receive treatment based on the collaborative care approach; the control group will receive 'care as usual'. Baseline and follow-up measurements (after 3, 6, 9, and 12 months) will be performed by means of questionnaires. The primary outcome measure is severity of depressive symptoms, as measured with the PHQ-9. The secondary outcome measure is the cost-effectiveness of these treatments according to the TiC-P, the EuroQol and the SF-36.DISCUSSION: Earlier research has indicated that depressive disorder is a chronic, mostly recurrent illness, which tends to cluster with physical comorbidity. Even though the treatment of depressive disorder based on the guidelines for depression is proven effective, these guidelines are often insufficiently adhered to. Collaborative care and 'Problem Solving Treatment' will be specifically tailored to patients with depressive disorders and evaluated in a general hospital setting in the Netherlands.",
keywords = "Antidepressive Agents, Chronic Disease, Comorbidity, Cost-Benefit Analysis, Depressive Disorder, Major, Humans, Netherlands, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't",
author = "Horn, {Eva K} and {van Benthem}, {Tjeerd B} and {Hakkaart-van Roijen}, Leona and {van Marwijk}, {Harm W J} and Beekman, {Aartjan T F} and Rutten, {Frans F} and {van der Feltz-Cornelis}, {Christina M}",
year = "2007",
month = "2",
day = "26",
doi = "10.1186/1472-6963-7-28",
language = "English",
volume = "7",
pages = "28",
journal = "BMC Health Services Research",
issn = "1472-6963",
publisher = "BioMed Central",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Cost-effectiveness of collaborative care for chronically ill patients with comorbid depressive disorder in the general hospital setting, a randomised controlled trial

AU - Horn, Eva K

AU - van Benthem, Tjeerd B

AU - Hakkaart-van Roijen, Leona

AU - van Marwijk, Harm W J

AU - Beekman, Aartjan T F

AU - Rutten, Frans F

AU - van der Feltz-Cornelis, Christina M

PY - 2007/2/26

Y1 - 2007/2/26

N2 - BACKGROUND: Depressive disorder is one of the most common disorders, and is highly prevalent in chronically ill patients. The presence of comorbid depression has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Early diagnosis and well-organized treatment of depression has a positive influence on these aspects. Earlier research in the USA has reported good results with regard to the treatment of depression with a collaborative care approach and an antidepressant algorithm. In the UK 'Problem Solving Treatment' has proved to be feasible. However, in the general hospital setting this approach has not yet been evaluated.METHODS/DESIGN: CC: DIM (Collaborative Care: Depression Initiative in the Medical setting) is a two-armed randomised controlled trial with randomisation at patient level. The aim of the trial is to evaluate the treatment of depressive disorder in general hospitals in the Netherlands based on a collaborative care framework, including contracting, 'Problem Solving Treatment', antidepressant algorithm, and manual-guided self-help. 126 outpatients with diabetes mellitus, chronic obstructive pulmonary disease, or cardiovascular diseases will be randomised to either the intervention group or the control group. Patients will be included if they have been diagnosed with moderate to severe depression, based on the DSM-IV criteria in a two-step screening method. The intervention group will receive treatment based on the collaborative care approach; the control group will receive 'care as usual'. Baseline and follow-up measurements (after 3, 6, 9, and 12 months) will be performed by means of questionnaires. The primary outcome measure is severity of depressive symptoms, as measured with the PHQ-9. The secondary outcome measure is the cost-effectiveness of these treatments according to the TiC-P, the EuroQol and the SF-36.DISCUSSION: Earlier research has indicated that depressive disorder is a chronic, mostly recurrent illness, which tends to cluster with physical comorbidity. Even though the treatment of depressive disorder based on the guidelines for depression is proven effective, these guidelines are often insufficiently adhered to. Collaborative care and 'Problem Solving Treatment' will be specifically tailored to patients with depressive disorders and evaluated in a general hospital setting in the Netherlands.

AB - BACKGROUND: Depressive disorder is one of the most common disorders, and is highly prevalent in chronically ill patients. The presence of comorbid depression has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Early diagnosis and well-organized treatment of depression has a positive influence on these aspects. Earlier research in the USA has reported good results with regard to the treatment of depression with a collaborative care approach and an antidepressant algorithm. In the UK 'Problem Solving Treatment' has proved to be feasible. However, in the general hospital setting this approach has not yet been evaluated.METHODS/DESIGN: CC: DIM (Collaborative Care: Depression Initiative in the Medical setting) is a two-armed randomised controlled trial with randomisation at patient level. The aim of the trial is to evaluate the treatment of depressive disorder in general hospitals in the Netherlands based on a collaborative care framework, including contracting, 'Problem Solving Treatment', antidepressant algorithm, and manual-guided self-help. 126 outpatients with diabetes mellitus, chronic obstructive pulmonary disease, or cardiovascular diseases will be randomised to either the intervention group or the control group. Patients will be included if they have been diagnosed with moderate to severe depression, based on the DSM-IV criteria in a two-step screening method. The intervention group will receive treatment based on the collaborative care approach; the control group will receive 'care as usual'. Baseline and follow-up measurements (after 3, 6, 9, and 12 months) will be performed by means of questionnaires. The primary outcome measure is severity of depressive symptoms, as measured with the PHQ-9. The secondary outcome measure is the cost-effectiveness of these treatments according to the TiC-P, the EuroQol and the SF-36.DISCUSSION: Earlier research has indicated that depressive disorder is a chronic, mostly recurrent illness, which tends to cluster with physical comorbidity. Even though the treatment of depressive disorder based on the guidelines for depression is proven effective, these guidelines are often insufficiently adhered to. Collaborative care and 'Problem Solving Treatment' will be specifically tailored to patients with depressive disorders and evaluated in a general hospital setting in the Netherlands.

KW - Antidepressive Agents

KW - Chronic Disease

KW - Comorbidity

KW - Cost-Benefit Analysis

KW - Depressive Disorder, Major

KW - Humans

KW - Netherlands

KW - Journal Article

KW - Multicenter Study

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.1186/1472-6963-7-28

DO - 10.1186/1472-6963-7-28

M3 - Article

VL - 7

SP - 28

JO - BMC Health Services Research

T2 - BMC Health Services Research

JF - BMC Health Services Research

SN - 1472-6963

ER -