Coverage with evidence development for medical devices in Europe: Can practice meet theory?

Mike Drummond, Carlo. Federici, Vivian. Reckers-Droog, Aleksandra Torbica, Carl Rudolf Blankart, Oriana Ciani, Zoltan Kalo, Sandor Kovacs, W.B.F. Brouwer

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Health economists have written extensively on the design and implementation of coverage with evidence development (CED) schemes and have proposed theoretical frameworks based on cost-effectiveness modeling and value of information analysis. CED may aid decision-makers when there is uncertainty about the (cost-)effectiveness of a new health technology at the time of reimbursement. Medical devices are potential candidates for CED schemes, as regulatory regimes do not usually require the same level of efficacy and safety data normally needed for pharmaceuticals. The purpose of this research is to assess whether the actual practice of CED for medical devices in Europe meets the theoretical principles proposed by health economists and whether theory and practice can be more closely aligned. Based on decision-makers' perceptions of the challenges associated with CED schemes, plus examples from the schemes themselves, we discuss a series of proposals for assessing the desirability of schemes, their design, implementation, and evaluation. These proposals, while reflecting the practical challenges with developing CED programs, embody many of the principles suggested by economists and should support decision-makers in dealing with uncertainty about the real-world performance of devices.
Original languageEnglish
Pages (from-to)179-194
JournalHealth Economics
Issue numberS1
Early online date26 Feb 2022
Publication statusPublished - Sept 2022

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