Cross aldol OPAL bioconjugation outcompetes intramolecular hemiaminal cyclisation of proline adjacent N-terminal α-oxo aldehydes at acidic pH

Afzaal Tufail; Saeed Akkad; Natasha Hatton; Nick Yates; Richard Spears; Tessa Keenan; Alison Parkin; Nathalie Yvonne Micheline Signoret; Martin Anthony Fascione

doi:10.1039/d3ra08776j

Cross aldol OPAL bioconjugation outcompetes intramolecular hemiaminal cyclisation of proline adjacent N-terminal α-oxo aldehydes at acidic pH

Afzaal Tufail, Saeed Akkad, Natasha Hatton, Nick Yates, Richard Spears, Tessa Keenan, Alison Parkin, Nathalie Yvonne Micheline Signoret^*, Martin Anthony Fascione^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3723-3729
Number of pages	7
Journal	RSC Advances
Volume	14
Issue number	6
Early online date	24 Jan 2024
DOIs	https://doi.org/10.1039/d3ra08776j
Publication status	E-pub ahead of print - 24 Jan 2024

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10.1039/d3ra08776jLicence: CC BY

Cross aldol OPAL bioconjugation outcompetes intramolecular hemiaminal cyclisation of proline adjacent N-terminal a-oxo aldehydes at acidic pH
© 2024 The Author(s).
Final published version, 1.17 MBLicence: CC BY

ChemGlycoSEPSIS: Chemical glycobiology for the study and exploitation of pseudaminic acid sugars in infectious diseases
Fascione, M. A. & O'Toole, P. J.
EUROPEAN COMMISSION
1/08/22 → 31/07/27
Project: Research project (funded) › Research

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title = "Cross aldol OPAL bioconjugation outcompetes intramolecular hemiaminal cyclisation of proline adjacent N-terminal α-oxo aldehydes at acidic pH",

author = "Afzaal Tufail and Saeed Akkad and Natasha Hatton and Nick Yates and Richard Spears and Tessa Keenan and Alison Parkin and Signoret, {Nathalie Yvonne Micheline} and Fascione, {Martin Anthony}",

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AU - Tufail, Afzaal

AU - Akkad, Saeed

AU - Hatton, Natasha

AU - Yates, Nick

AU - Spears, Richard

AU - Keenan, Tessa

AU - Parkin, Alison

AU - Signoret, Nathalie Yvonne Micheline

AU - Fascione, Martin Anthony

PY - 2024/1/24

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DO - 10.1039/d3ra08776j

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JF - RSC Advances

IS - 6

ER -

Cross aldol OPAL bioconjugation outcompetes intramolecular hemiaminal cyclisation of proline adjacent N-terminal α-oxo aldehydes at acidic pH

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Projects

ChemGlycoSEPSIS: Chemical glycobiology for the study and exploitation of pseudaminic acid sugars in infectious diseases

Cite this