Research output: Contribution to journal › Article › peer-review
Journal | Acta Crystallographica Section F: Structural Biology and Crystallization Communications |
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Date | E-pub ahead of print - 22 Feb 2012 |
Date | Published (current) - 2012 |
Issue number | Pt 3 |
Volume | 68 |
Number of pages | 4 |
Pages (from-to) | 333-336 |
Early online date | 22/02/12 |
Original language | English |
Dihydrouridine synthases catalyse the reduction of uridine to dihydrouridine in the D-loop and variable loop of tRNA. The human dihydrouridine synthase HsDus2L has been implicated in the development of pulmonary carcinogenesis. Here, the purification, crystallization and preliminary X-ray characterization of the HsDus2L catalytic domain are reported. The crystals belonged to space group P2(1) and contained a single molecule of HsDus2L in the asymmetric unit. A complete data set was collected to 1.9 Å resolution using synchrotron radiation.
© 2012 International Union of Crystallography
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