Projects per year
Abstract
The catalyst which is used in the signal amplification by reversible exchange (SABRE) process facilitates substrate hyperpolarisation while acting to speed up the rate of relaxation. Consequently, the lifetime over which the hyperpolarised contrast agent is visible is drastically reduced. We show that the addition of a chelating ligand, such as bipyridine, rapidly deactivates the SABRE catalyst thereby lengthening the agent's relaxation times and improving the potential of SABRE for diagnostic MRI.
Original language | English |
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Pages (from-to) | 9857-9859 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 51 |
Early online date | 13 May 2015 |
DOIs | |
Publication status | Published - 2015 |
Projects
- 1 Finished
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Hyperpolarisation using SABRE as a new tool for imaging
Duckett, S. B. (Principal investigator) & Green, G. G. R. (Co-investigator)
1/10/12 → 31/03/19
Project: Research project (funded) › Research