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From the same journal

Chemical communications (Journal)
Lianne Irene Willems (Reviewer)
29 Jun 2019 → 11 Oct 2019
Activity: Publication peer-review and editorial work › Journal peer review

Research output: Contribution to journal › Article

Published copy (DOI)

10.1039/C5CC01896J

Author(s)

Department/unit(s)

Publication details

Journal	Chemical Communications
Date	E-pub ahead of print - 13 May 2015
Date	Published (current) - 2015
Volume	51
Number of pages	3
Pages (from-to)	9857-9859
Early online date	13/05/15
Original language	English

Abstract

The catalyst which is used in the signal amplification by reversible exchange (SABRE) process facilitates substrate hyperpolarisation while acting to speed up the rate of relaxation. Consequently, the lifetime over which the hyperpolarised contrast agent is visible is drastically reduced. We show that the addition of a chelating ligand, such as bipyridine, rapidly deactivates the SABRE catalyst thereby lengthening the agent's relaxation times and improving the potential of SABRE for diagnostic MRI.

Projects

Hyperpolarisation using SABRE as a new tool for imaging
Project: Research project (funded) › Research

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By the same authors

Delivering strong ¹H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange

Harnessing polarisation transfer to indazole and imidazole through signal amplification by reversible exchange to improve their NMR detectability

Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by 1H-NMR spectrscopy

Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by ¹H NMR spectroscopy

Molecular MRI in the Earth's Magnetic Field Using Continuous Hyperpolarization of a Biomolecule in Water

From the same journal

Rational redox tuning of transition metal sites: Learning from superoxide reductase

Delineating the critical role of acid additives in Mn-catalysed C-H bond functionalisation processes

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Carbon nitride as a ligand: edge-site coordination of ReCl(CO)₃-fragments to g-C₃ N₄

Unexpected, photochemically induced activation of the tetrabutylammonium cation by hexachloroplatinate(iv)

From the same journal

Chemical communications (Journal)