Default Mode Network Engagement Beyond Self-Referential Internal Mentation

Deniz Vatansever; Anne E Manktelow; Barbara J Sahakian; David K Menon; Emmanuel A Stamatakis

doi:10.1089/brain.2017.0489

Default Mode Network Engagement Beyond Self-Referential Internal Mentation

Deniz Vatansever, Anne E Manktelow, Barbara J Sahakian, David K Menon, Emmanuel A Stamatakis

Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

The default mode network (DMN) is typically associated with off-task internal mentation, or with goal-oriented tasks that require self-referential processing such as autobiographical planning. However, recent reports suggest a broader involvement of the DMN in higher cognitive processing. In line with this view, we report global connectivity changes centred on the main DMN hubs of precuneus and posterior cingulate cortex during an fMRI-based visuospatial version of the Tower of London planning task. Importantly, functional connectivity of these regions and the left caudate shows a significant relationship with faster reaction time to correct responses only during the high-demand planning condition, thus offering further evidence for the DMN's engagement during visuospatial planning. The results of this study not only provide robust evidence against the widely held notion of DMN disengagement during goal-oriented, attention-demanding, externally-directed tasks, but also support its involvement in a broader cognitive context with a memory-related role that extends beyond self-referential, internally-directed mentation.

Original language	English
Journal	Brain Connectivity
Early online date	24 Jan 2018
DOIs	https://doi.org/10.1089/brain.2017.0489
Publication status	E-pub ahead of print - 24 Jan 2018

Bibliographical note

This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details

Access to Document

10.1089/brain.2017.0489

DV_BrainConnectivity_Accepted_Manuscript_PDF
This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details
Accepted author manuscript, 7.48 MBLicence: Unspecified

Cite this

@article{84649945aa0d479496a8c94ad73ae6ac,

title = "Default Mode Network Engagement Beyond Self-Referential Internal Mentation",

abstract = "The default mode network (DMN) is typically associated with off-task internal mentation, or with goal-oriented tasks that require self-referential processing such as autobiographical planning. However, recent reports suggest a broader involvement of the DMN in higher cognitive processing. In line with this view, we report global connectivity changes centred on the main DMN hubs of precuneus and posterior cingulate cortex during an fMRI-based visuospatial version of the Tower of London planning task. Importantly, functional connectivity of these regions and the left caudate shows a significant relationship with faster reaction time to correct responses only during the high-demand planning condition, thus offering further evidence for the DMN's engagement during visuospatial planning. The results of this study not only provide robust evidence against the widely held notion of DMN disengagement during goal-oriented, attention-demanding, externally-directed tasks, but also support its involvement in a broader cognitive context with a memory-related role that extends beyond self-referential, internally-directed mentation.",

author = "Deniz Vatansever and Manktelow, {Anne E} and Sahakian, {Barbara J} and Menon, {David K} and Stamatakis, {Emmanuel A}",

note = "This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details",

year = "2018",

month = jan,

day = "24",

doi = "10.1089/brain.2017.0489",

language = "English",

journal = "Brain Connectivity",

issn = "2158-0022",

publisher = "Mary Ann Liebert Inc.",

}

TY - JOUR

T1 - Default Mode Network Engagement Beyond Self-Referential Internal Mentation

AU - Vatansever, Deniz

AU - Manktelow, Anne E

AU - Sahakian, Barbara J

AU - Menon, David K

AU - Stamatakis, Emmanuel A

N1 - This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details

PY - 2018/1/24

Y1 - 2018/1/24

N2 - The default mode network (DMN) is typically associated with off-task internal mentation, or with goal-oriented tasks that require self-referential processing such as autobiographical planning. However, recent reports suggest a broader involvement of the DMN in higher cognitive processing. In line with this view, we report global connectivity changes centred on the main DMN hubs of precuneus and posterior cingulate cortex during an fMRI-based visuospatial version of the Tower of London planning task. Importantly, functional connectivity of these regions and the left caudate shows a significant relationship with faster reaction time to correct responses only during the high-demand planning condition, thus offering further evidence for the DMN's engagement during visuospatial planning. The results of this study not only provide robust evidence against the widely held notion of DMN disengagement during goal-oriented, attention-demanding, externally-directed tasks, but also support its involvement in a broader cognitive context with a memory-related role that extends beyond self-referential, internally-directed mentation.

AB - The default mode network (DMN) is typically associated with off-task internal mentation, or with goal-oriented tasks that require self-referential processing such as autobiographical planning. However, recent reports suggest a broader involvement of the DMN in higher cognitive processing. In line with this view, we report global connectivity changes centred on the main DMN hubs of precuneus and posterior cingulate cortex during an fMRI-based visuospatial version of the Tower of London planning task. Importantly, functional connectivity of these regions and the left caudate shows a significant relationship with faster reaction time to correct responses only during the high-demand planning condition, thus offering further evidence for the DMN's engagement during visuospatial planning. The results of this study not only provide robust evidence against the widely held notion of DMN disengagement during goal-oriented, attention-demanding, externally-directed tasks, but also support its involvement in a broader cognitive context with a memory-related role that extends beyond self-referential, internally-directed mentation.

U2 - 10.1089/brain.2017.0489

DO - 10.1089/brain.2017.0489

M3 - Article

C2 - 29366339

SN - 2158-0022

JO - Brain Connectivity

JF - Brain Connectivity

ER -