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Deregulated over expression of FOXP1 protein in diffuse large B-cell lymphoma does not occur as a result of gene rearrangement

Research output: Contribution to journalLetterpeer-review


  • Sharon L. Barrans
  • James A. L. Fenton
  • Roland Ventura
  • Alex Smith
  • Alison H. Banham
  • Andrew S. Jack


Publication details

JournalHaematologica-The hematology journal
DatePublished - Jun 2007
Issue number6
Number of pages2
Pages (from-to)863-864
Original languageEnglish


Strong uniform expression of FOXP1 protein occurs in a subgroup of non-germinal centre (GC) diffuse large B-cell lymphomas (DLBCL). We have investigated gene rearrangement as a potential mechanism for deregulated expression of FOXP1 however, using FISH FOXP1 translocations were not found in any case with over-expression of the protein.

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