Desulfonylation of amides using samarium iodide

H  Knowles; A F  Parsons; R M  Pettifer

Desulfonylation of amides using samarium iodide

H Knowles, A F Parsons, R M Pettifer

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The desulfonylation of N-sulfonyl amides can be achieved in reasonable to excellent yield by reaction with samarium(II) iodide (SmI2) in THF at room temperature. Deprotection of acyclic and cyclic amides bearing aryl and alkylsulfonyl groups is possible.

Original language	English
Pages (from-to)	271
Number of pages	3
Journal	Synlett
Issue number	3
Publication status	Published - Mar 1997

Keywords

samarium (II) iodide
desulfonylation
amide
CLEAVAGE

Cite this

@article{cc9d0e46a2ee407f8f218cd8ed731259,

title = "Desulfonylation of amides using samarium iodide",

abstract = "The desulfonylation of N-sulfonyl amides can be achieved in reasonable to excellent yield by reaction with samarium(II) iodide (SmI2) in THF at room temperature. Deprotection of acyclic and cyclic amides bearing aryl and alkylsulfonyl groups is possible.",

keywords = "samarium (II) iodide, desulfonylation, amide, CLEAVAGE",

author = "H Knowles and Parsons, {A F} and Pettifer, {R M}",

year = "1997",

month = mar,

language = "English",

pages = "271",

journal = "Synlett",

issn = "1437-2096",

publisher = "Georg Thieme Verlag",

number = "3",

}

TY - JOUR

T1 - Desulfonylation of amides using samarium iodide

AU - Knowles, H

AU - Parsons, A F

AU - Pettifer, R M

PY - 1997/3

Y1 - 1997/3

N2 - The desulfonylation of N-sulfonyl amides can be achieved in reasonable to excellent yield by reaction with samarium(II) iodide (SmI2) in THF at room temperature. Deprotection of acyclic and cyclic amides bearing aryl and alkylsulfonyl groups is possible.

AB - The desulfonylation of N-sulfonyl amides can be achieved in reasonable to excellent yield by reaction with samarium(II) iodide (SmI2) in THF at room temperature. Deprotection of acyclic and cyclic amides bearing aryl and alkylsulfonyl groups is possible.

KW - samarium (II) iodide

KW - desulfonylation

KW - amide

KW - CLEAVAGE

M3 - Article

SN - 1437-2096

SP - 271

JO - Synlett

JF - Synlett

IS - 3

ER -