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Desulfonylation of amides using samarium iodide
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| Journal | Synlett |
|---|---|
| Date | Published - Mar 1997 |
| Issue number | 3 |
| Number of pages | 3 |
| Pages (from-to) | 271 |
| Original language | English |
Abstract
The desulfonylation of N-sulfonyl amides can be achieved in reasonable to excellent yield by reaction with samarium(II) iodide (SmI2) in THF at room temperature. Deprotection of acyclic and cyclic amides bearing aryl and alkylsulfonyl groups is possible.
- samarium (II) iodide, desulfonylation, amide, CLEAVAGE
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